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How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease
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The article was published on 2010-01-01 and is currently open access. It has received 1442 citations till now. The article focuses on the topics: Tobacco smoke.read more
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Journal ArticleDOI
The Effect of NNK, A Tobacco Smoke Carcinogen, on the miRNA and Mismatch DNA Repair Expression Profiles in Lung and Head and Neck Squamous Cancer Cells
Sotirios G. Doukas,Sotirios G. Doukas,Dimitra P. Vageli,George Lazopoulos,Demetrios A. Spandidos,Clarence T. Sasaki,Aristidis Tsatsakis +6 more
TL;DR: Novel findings are provided that deregulated miR-21,miR-155, and miR -422a and MMR gene expression patterns may be valuable biomarkers for lung and head and neck squamous cell cancer progression in smokers.
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History repeats itself: Role of characterizing flavors on nicotine use and abuse.
Theresa Patten,Mariella De Biasi +1 more
TL;DR: This review addresses the possibility that characterizing flavors make nicotine more appealing, rewarding and addictive and discusses ways in which preclinical and clinical studies could improve the understanding of the mechanisms by which flavors may alter nicotine reward and reinforcement.
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Non-cigarette tobacco and the lung.
TL;DR: Though it is clear that cigar and waterpipe tobacco smoking are probably as dangerous to health as cigarette smoking, there is an opinion among users that the health risks are less compared to cigarettes, particularly true in younger age groups.
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Effects of Electronic Nicotine Delivery System on Larynx: Experimental Study.
Ziya Saltürk,Çağlar Çakır,Gürcan Sünnetçi,Yavuz Atar,Tolgar Lütfi Kumral,Guven Yildirim,Güler Berkiten,Yavuz Uyar +7 more
TL;DR: Exposure to ENDS for 4 weeks caused hyperplasia and metaplasia of the laryngeal mucosa of rats but this was not significant statistically, suggesting that further studies with larger cohort and longer duration are required to evaluate long-term effects.
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Smoking cessation and mortality among middle-aged and elderly Chinese in Singapore: the Singapore Chinese Health Study
TL;DR: Significant reduction in risk of total mortality, specifically for lung cancer mortality, can be achieved within 5 years of smoking cessation, and this result for new quitters was of borderline significance.