Journal ArticleDOI
Hypertension and Severe Hyperkalaemia Associated with Suppression of Renin and Aldosterone and Completely Reversed by Dietary Sodium Restriction
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This article is published in Australasian annals of medicine.The article was published on 1970-11-01. It has received 172 citations till now. The article focuses on the topics: Natriuresis & Aldosterone.read more
Citations
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Journal ArticleDOI
Renin, angiotensin and aldosterone system in pathogenesis and management of hypertensive vascular disease
TL;DR: Longitudinal studies indicate that patients with low renin essential hypertension appear to be protected from the development of strokes and heart attacks despite similar hypertension and cardiac enlargement and a higher age.
Journal ArticleDOI
Mineralocorticoid-resistant renal hyperkalemia without salt wasting (type II pseudohypoaldosteronism): role of increased renal chloride reabsorption.
TL;DR: It is suggested that the primary abnormality in this syndrome increases the reabsorptive avidity of the distal nephron for chloride, which limits the sodium and mineralocorticoid-dependent voltage driving force for potassium and hydrogen ion secretion, resulting in hyperkalemia and acidosis and augments distal sodium chloride reabsorption resulting inhyperchloremia, volume expansion, hyporeninemia, and hypertension.
Journal ArticleDOI
Multilocus Linkage of Familial Hyperkalaemia and Hypertension, Pseudohypoaldosteronism Type II, to Chromosomes 1q31-42 and 17p11-q21
T A Mansfield,David B. Simon,Zvi Farfel,Margaret J. Bia,Joseph R. Tucci,M Lebel,Michael Gutkin,B Vialettes,M A Christofilis,R Kauppinen-Makelin,Haim Mayan,Neil Risch,Richard P. Lifton +12 more
TL;DR: Analysis of linkage in eight PHAII families showing autosomal dominant transmission demonstrates locus heterogeneity of this trait, and finds the chromosome-17 locus overlaps a syntenic interval in rat that contains a blood pressure quantitative trait locus (QTL).
Journal ArticleDOI
Syndrome of hypertension and hyperkalemia with normal glomerular filtration rate.
TL;DR: Syndrome, parfois familial, associant une hypertension dependant du volume, une hyperkaliemie, une acidemie et des taux faibles de renine, sont rapidement reversibles sous diuretiques thiazidiques ou sont lentements reversibles par regime of restriction sodee.
Journal ArticleDOI
The association of nephrolithiasis with hypertension and obesity: a review.
TL;DR: The possibility that common pathophysiologic mechanisms underly these diseases is intriguing, and if better understood, could potentially lead to better therapies for stone prevention.
References
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Journal ArticleDOI
Hyperplasia of the juxtaglomerular complex with hyperaldosteronism and hypokalemic alkalosis. A new syndrome.
TL;DR: In this article, a new syndrome, characterized by hypertrophy and hyperplasia of the juxtaglomerular apparatus of the kidneys, aldosteronism resulting from adrenal cortical hyper-plasia, and persistently normal blood pressure is described in two patients.
Journal ArticleDOI
Double isotope derivative assay of aldosterone in biological extracts.
TL;DR: This report includes a detailed description of the method, assay results for human urine and dog adrenal vein plasma, and a critical evaluation of the specificity, precision, and accuracy of this technique.
Journal ArticleDOI
Improved Assay Methods for Renin "Concentration" and "Activity" in Human Plasma Methods Using Selective Denaturation Of Renin Substrate
TL;DR: Simplified methods are described for the measurement of human plasma renin “concentration” (PRC) and “activity’ (PRA) based on the denaturation of renin substrate in which separation and concentration steps are avoided and recovery of ren in is complete.
Journal ArticleDOI
A diurnal rhythm in plasma renin activity in man.
TL;DR: Attention is focused for the first time on the question of whether there might be a consistent diurnal rhythm in plasma renin activity, which is a function of the time of day rather than the duration of upright posture.
Journal ArticleDOI
The effect of angiotensin ii on the blood pressure in humans with hypertensive disease.
Norman M Kaplan,Jack G. Silah +1 more
TL;DR: The results suggest that the pressor responsiveness to angiotensin may be a useful clinical test for the diagnosis of renovascular hypertension.
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