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Journal ArticleDOI

Hypoxic Pulmonary Vasoconstriction and Gas Exchange During Exercise in Chronic Obstructive Pulmonary Disease

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TLDR
It is postulate that most of the VA/Q improvement that exercise may induce in patients with COPD, as it is shown here, is due to improvement in the ventilation distribution, and Interestingly, this VA/ Q improvement was not paralleled by a significant decrease of P(A-a)O2.
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This article is published in Chest.The article was published on 1990-02-01. It has received 153 citations till now. The article focuses on the topics: Pulmonary hypertension & Hypoxic pulmonary vasoconstriction.

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Special article2015 ESC/ERS Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension

TL;DR: This article is being published concurrently in the European Heart Journal and the European Respiratory Journal and is identical except for minor stylistic and spelling differences in keeping with each journal’s style.
References
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Journal ArticleDOI

Normal standards for an incremental progressive cycle ergometer test.

TL;DR: The VO2 increased linearly with power throughout the test; in an individual subject, the intercept of this relationship was positively influenced by weight and height, and the maximal tidal volume was related to vital capacity.
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Ventilation-perfusion inequality in chronic obstructive pulmonary disease.

TL;DR: The observed patterns of VA/Q inequality and shunt accounted for all of the hypoxemia at rest and during exercise, and there was therefore no evidence forHypoxemia caused by diffusion impairment.
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Pulmonary gas exchange

TL;DR: In this paper, the authors considered the volume of fresh air reaching the alveoli per breath is 150 mL less than tidal volume, and showed that alveolar, not minute ventilation, is critical to gas exchange.
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Limits on VA/Q distributions from analysis of experimental inert gas elimination.

TL;DR: It is found that the variability among distributions with compatible retentions depends greatly on the particular set of data.
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