Journal ArticleDOI
Identification of embryonic motoneurons in vitro: their survival is dependent on skeletal muscle
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This article is published in Brain Research.The article was published on 1980-05-26. It has received 119 citations till now. The article focuses on the topics: Skeletal muscle.read more
Citations
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Journal ArticleDOI
Fluorescent carbocyanine dyes allow living neurons of identified origin to be studied in long-term cultures
Marcia G. Honig,Richard I. Hume +1 more
TL;DR: The results indicate that preganglionic neurons can survive in the absence of their target cells and that several aspects of their differentiation in the presence of target appear normal.
Journal ArticleDOI
Dil and DiO: versatile fluorescent dyes for neuronal labelling and pathway tracing
Marcia G. Honig,Richard I. Hume +1 more
TL;DR: The properties of carbocyanine dyes are reviewed and some of their uses and advantages are pointed out and several exciting advances in developmental neurobiology are allowed.
Journal ArticleDOI
Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons
TL;DR: It is suggested that NGF-R mediates a trophic or axonal guidance function for developing and regenerating spinal cord motoneurons.
Journal ArticleDOI
New Neuronal Growth Factors
TL;DR: Experiments in vivo indicate that NGF can reverse naturally occurring as well as experimentally induced cell death in sympathetic and sensory neurons; moreover, anti-NGF antibodies in vivo can block the development of the sympathetic nervous system.
Book ChapterDOI
Naturally Occurring Neuronal Death in Vertebrates
TL;DR: In early embryos of lower vertebrates one finds primitive sensory neurons in the dorsal part of the spinal cord, the Rohon-Beard cells, which undergo regression when the spinal ganglia take over their function.
References
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Journal ArticleDOI
A new specific, sensitive and non-carcinogenic reagent for the demonstration of horseradish peroxidase
TL;DR: DAB staining of transported HRP in neurons has developed into a powerful neuroanatomical tool for labelling the cells of origin of pathways in the central nervous system and may be responsible for the decreased availability of good quality DAB.
Journal ArticleDOI
Cell death in the development of the lateral motor column of the chick embryo.
TL;DR: Arguments are presented in support of the hypothesis that the naturally occurring cell death in the l.m.c. is due to the failure of their axons to survive in a competion process at the periphery, and observations of the time pattern of muscle differentiation and their neurotization in the leg further endorse this hypothesis.
Journal ArticleDOI
The formation of synapses in striated muscle during development.
Max R. Bennett,A. G. Pettigrew +1 more
TL;DR: A study has been made of the formation of synapses in developing striated muscles which receive either a focal (the rat hemidiaphragm) or a distributed innervation using histological, ultrastructural and electrophysiological techniques.
Journal ArticleDOI
Reduction of the naturally occurring motor neuron loss by enlargement of the periphery
TL;DR: The data do not permit a decision between the two alternatives: competition for synaptic sites or for a trophic agent, and should be replaced by the term “hypothanasia.”
Journal ArticleDOI
The distribution of motoneurones supplying chick hind limb muscles.
TL;DR: It is concluded that motoneurone position is most closely correlated with ontogenetic events presumaeriphery and it can be inferred that the central connexions onto motOneurones, responsible for their proper activation, cannot be achieved by a simple mechanism based largely on the position of the mot oneurone soma.