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Patent

Immobilized enzymes, processes for preparing same and use thereof

TLDR
In this paper, the authors used amorphous, approximately spherical silica particles obtained from synthetic calcium silicate to bound enzymes to an inorganic carrier by an amino group through a bifunctional spacer.
Abstract
Immobilized enzymes covalently bound to an inorganic carrier by an amino group through a bifunctional spacer have improved properties when the carrier is formed of amorphous, approximately spherical silica particles obtained from synthetic calcium silicate. The silica particles have an average particle size of from 15 to 80 μm, an apparent particle volume of from 1.3 to 3 cm3 /g, and a specific surface area of from 250 to 800 m2 /g.

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Recurrent gene fusions in prostate cancer

TL;DR: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described in this paper, where compositions and methods having utility in prostate diagnosis, research, and therapy are also provided.
Patent

Egfr and kras mutations

TL;DR: In this article, a method for detecting mutations in Epidermal Growth Factor Receptor (EGFR) and KRAS and methods of detecting such mutations as well as prognostic methods method for identifying a tumors that are susceptible to anticancer therapy such as chemotherapy and/or kinase inhibitor treatment.
Patent

Methods for treating cancer resistant to erbb therapeutics

TL;DR: In this article, methods for treating cancer that is resistant to treatment with an anti-ErbB therapeutic agent and which is associated with an activating MET gene mutation or a MET gene amplification are presented.
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Anti-fgfr3 antibodies and methods using same

TL;DR: In this paper, the authors provide FGFR3 antibodies and compositions comprising and methods of using these antibodies, as well as compositions and methods for using these antibody types for medical applications.
Patent

Sensor using a field effect transistor and method of fabricating the same

TL;DR: In this paper, a sensor using a field effect transistor is described, which includes a gate electrode, a reactive monomolecular film formed on the surface of the gate electrode and a sensing material fixed on the gate by the chemical bond.
References
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Enzymatic hydrolysis of cellulose to glucose lung immobilized ?-glucosidase

TL;DR: Increased yields of glucose and greater conversions of cellobiose of glucose were observed when the reaction systems contained supplemental immobilized β‐glucosidase.
Patent

Titanium impregnated silica-chromium catalysts

TL;DR: In this article, a silica hydrogel is prepared and dried in the presence of a pore preserving agent after which a titanium compound is anhydrously incorporated therewith.
Patent

Novel amorphous silica

TL;DR: Amorphous silicas having a crystalline appearance, at least two surfaces in symmetric relation, a length of about 1 to about 500μ and a thickness of about 50 A to about 1μ, the length being at least about 10 times the thickness, the amorphous silica being in the form of primary particles, secondary particles, aqueous dispersions of the particles and shaped bodies as discussed by the authors.
Patent

Whole cell enzyme composition containing fumed silica

TL;DR: In this paper, a dimensionally stable glucose isomerase composition having improved hydraulic characteristics and suitable for continuous column isomerization of glucose to fructose is produced by incorporating a low density, high surface area silica such as fumed silica into wet whole microorganism cells, and extruding and drying the cells to obtain the cells in particulate form.