Impact of mitral valve annuloplasty on mortality risk in patients with mitral regurgitation and left ventricular systolic dysfunction
Audrey H. Wu,Keith D. Aaronson,Steven F. Bolling,Francis D. Pagani,Kathy Welch,Todd M. Koelling +5 more
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TLDR
There is no clearly demonstrable mortality benefit conferred by MVA for significant MR with severe LV dysfunction, and a prospective randomized control trial is warranted for further study of mortality with MVA in this population.About:
This article is published in Journal of the American College of Cardiology.The article was published on 2005-02-01 and is currently open access. It has received 637 citations till now. The article focuses on the topics: Mitral valve annuloplasty & Mitral regurgitation.read more
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Journal ArticleDOI
Sucesso da terapêutica de ressincronização cardíaca num doente com insuficiência cardíaca e regurgitação mitral secundária a doença isquémica: Importância do septal flash
Renata Gomes,Regina Ribeiras,Pedro Carmo,Sónia Lima,Francisco Morgado,E Horta,Raquel Gouveia,Aniceto Silva +7 more
TL;DR: Na nossa experiencia, a presenca deste movimento septal que tem como substrato dessincronia intraventricular de predominio radial, parece ser um marcador de resposta a CRT, pelo que, ponderados os riscos/beneficios da terapeutica cirurgica mitral sem revascularizacao associada, optou-se por esta ultima.
Book ChapterDOI
Future Perspectives of Catheter-Based Treatment in Valvular Heart Diseases
Hans R. Figulla,Alexander Lauten +1 more
TL;DR: In this chapter the potentials and drawbacks of the present and emerging TVT technology are focused on and some of the future lines of research and applications are outlined.
Editorial Comment The Treatment of Ischemic Heart Failure With Surgical Ventricular Restoration (SVR): New Evidence of Benefit
TL;DR: Experimental and clinical studies support the hypothesis that increased ventricular volume is directly related to increased morbidity and mortality and suggest that surgical ventricular restoration, which can achieve a greater amount of volume reduction than medical therapy, may lead to a corresponding greater reduction in mortality.
References
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The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators.
Bertram Pitt,Faiez Zannad,Willem J. Remme,Robert J. Cody,Alain Castaigne,Alfonso Perez,Jolie Palensky,Janet Wittes +7 more
TL;DR: Blockade of aldosterone receptors by spironolactone, in addition to standard therapy, substantially reduces the risk of both morbidity and death among patients with severe heart failure.
Journal ArticleDOI
Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction.
Arthur J. Moss,Wojciech Zareba,W. Jackson Hall,Helmut U. Klein,David J. Wilber,David S. Cannom,James P. Daubert,Steven L. Higgins,Mary W. Brown,Mark L. Andrews +9 more
TL;DR: In patients with a prior myocardial infarction and advanced left ventricular dysfunction, prophylactic implantation of a defibrillator improves survival and should be considered as a recommended therapy.
Journal ArticleDOI
Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure.
Michael R. Bristow,Leslie A. Saxon,John P. Boehmer,Steven K. Krueger,David A. Kass,Teresa De Marco,Peter E. Carson,Lorenzo DiCarlo,David L. DeMets,Bill G. White,Dale W DeVries,Arthur M. Feldman +11 more
TL;DR: In this paper, the authors tested the hypothesis that prophylactic cardiac-resynchronization therapy in the form of biventricular stimulation with a pacemaker with or without a defibrillator would reduce the risk of death and hospitalization among patients with advanced chronic heart failure and intraventricular conduction delays.
Journal ArticleDOI
The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure
Bertram Pitt,Faiez Zannad,Willem J. Remme,Robert J. Cody,Alain Castaigne,Alfonso Perez,Jolie Palensky,Janet Wittes +7 more