Journal ArticleDOI
In vivo multiple color lymphatic imaging using upconverting nanocrystals
Hisataka Kobayashi,Nobuyuki Kosaka,Mikako Ogawa,Nicole Y. Morgan,Paul D. Smith,Christopher B. Murray,Xingchen Ye,Josh Collins,G. Ajith Kumar,Howard Bell,Peter L. Choyke +10 more
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TLDR
Upconverting nanocrystals are unique nano-sized particles that emit light at shorter wavelengths after excitation in the near infrared that dramatically reduces background autofluorescence in in vivo two color lymphatic imaging for depicting the lymphatic channels and nodes.Abstract:
Upconverting nanocrystals are unique nano-sized particles that emit light at shorter wavelengths (visible and near infrared) after excitation in the near infrared that dramatically reduces background autofluorescence in in vivo two color lymphatic imaging for depicting the lymphatic channels and nodes.read more
Citations
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Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics
TL;DR: Applications in Theranostics Guanying Chen,*,†,‡ Hailong Qiu,*,‡ and Xiaoyuan Chen.
Journal ArticleDOI
Upconversion luminescent materials: advances and applications.
Journal ArticleDOI
Upconversion nanophosphors for small-animal imaging
Jing Zhou,Zhuang Liu,Fuyou Li +2 more
TL;DR: In this critical review, recent reports regarding the synthesis of water-soluble UCNPs and their surface modification and bioconjugation chemistry are summarized and the applications ofUCNPs for small-animal imaging, including tumor-targeted imaging, lymphatic imaging, vascular imaging and cell tracking are reviewed in detail.
Journal ArticleDOI
Upconversion nanoparticles in biological labeling, imaging, and therapy
TL;DR: Recent developments in optical biolabeling and bio-imaging involving upconversion nanoparticles are reviewed, simultaneously bringing to the forefront the desirable characteristics, strengths and weaknesses of these luminescent nanomaterials.
References
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Imaging in the era of molecular oncology
TL;DR: Advances in experimental and clinical imaging are likely to improve how cancer is understood at a systems level and should enable doctors not only to locate tumours but also to assess the activity of the biological processes within these tumours and to provide 'on the spot' treatment.
Journal ArticleDOI
Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping
Sungjee Kim,Yong Taik Lim,Yong Taik Lim,Edward G. Soltesz,Alec M. De Grand,Jaihyoung Lee,Akira Nakayama,J. Anthony Parker,Tomislav Mihaljevic,Rita G. Laurence,Delphine M. Dor,Lawrence H. Cohn,Moungi G. Bawendi,John V. Frangioni +13 more
TL;DR: It is demonstrated that the fluorescence emission of type II quantum dots can be tuned into the near infrared while preserving absorption cross-section, and that a polydentate phosphine coating renders them soluble, disperse and stable in serum.
Journal ArticleDOI
High-Quality Sodium Rare-Earth Fluoride Nanocrystals: Controlled Synthesis and Optical Properties
TL;DR: Photoluminescent measurements indicate that the value of I610/I590 and the overall emission intensity of the NaEuF4 nanocrystals are highly correlative with the symmetries of the Eu3+ ions in both the lattice and the surface.
Journal ArticleDOI
Upconversion multicolor fine-tuning: visible to near-infrared emission from lanthanide-doped NaYF4 nanoparticles.
Feng Wang,Xiaogang Liu +1 more
TL;DR: A general approach to fine-tuning the upconversion emission colors, based upon a single host source of NaYF4 nanoparticles doped with Yb3+, Tm3+, and Er3+, is presented.
Journal ArticleDOI
Upconversion fluorescence imaging of cells and small animals using lanthanide doped nanocrystals.
TL;DR: Polyethyleneimine coated NaYF(4):Yb,Er nanoparticles were synthesized, which produce very strong upconversion fluorescence when excited at 980 nm by a NIR laser, and were shown to be stable in physiologic buffered saline (PBS), non-toxic to bone marrow stem cells, and resistant to photo-bleaching.
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Recent advances in the chemistry of lanthanide-doped upconversion nanocrystals
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