Incidence and Risk Factors of Deep Vein Thrombosis in Hospitalized COVID-19 Patients.
Yuan Yu,Jie Tu,Bingxin Lei,Huaqing Shu,Xiaojing Zou,Ruiting Li,Chaolin Huang,Yali Qu,You Shang +8 more
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TLDR
This study revealed that a high number of patients with COVID-19 developed DVT, particularly in critically ill patients with high D-dimer levels who required no anticoagulant medication.Abstract:
Deep vein thrombosis (DVT) is prevalent in patients with coronavirus disease 2019 (COVID-19). However, the risk factors and incidence rate of DVT remains elusive. Here, we aimed to assess the incidence rate and risk factors of DVT. All patients diagnosed with COVID-19 and performed venous ultrasound by ultrasound deparment between December 2019 and April 2020 in Wuhan Jin Yin-tan hospital were enrolled. Demographic information and clinical features were retrospectively collected. Notably, a comparison between the DVT and the non-DVT groups was explored. The incidence rate of venous thrombosis was 35.2% (50 patients out of 142). Moreover, the location of thrombus at the proximal extremity veins was 5.6% (n = 8), while at distal extremity veins was 35.2% (n = 50) of the patients. We also noted that patients with DVT exhibited a high level of D-dimer (OR 10.9 (95% CI, 3.3-36.0), P < 0.001), were admitted to the intensive care unit (OR 6.5 (95% CI, 2.1-20.3), P = 0.001), a lower usage of the anticoagulant drugs (OR 3.0 (95% CI, 1.1-7.8), P < 0.001). Finally, this study revealed that a high number of patients with COVID-19 developed DVT. This was observed particularly in critically ill patients with high D-dimer levels who required no anticoagulant medication.read more
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Venous thromboembolism in COVID-19: A systematic review and meta-analysis.
Anastasios Kollias,Konstantinos G. Kyriakoulis,Styliani Lagou,Evangelos Kontopantelis,George S. Stergiou,Konstantinos N. Syrigos +5 more
TL;DR: In this paper, a systematic review in PubMed/EMBASE of studies reporting severe coronavirus disease 2019 (COVID-19) is associated with increased risk of venous thromboembolism events (VTE).
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Asthma in patients with coronavirus disease 2019: A systematic review and meta-analysis.
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TL;DR: In this paper, the authors explored the prevalence of asthma in patients with COVID-19 and the relationship between asthma and patients with COPD with poor outcomes and found that asthma was associated with reduced risk of poor outcomes.
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TL;DR: In this paper, the authors performed an analysis of 160 consecutive patients with confirmed COVID-19 infection admitted to the Respiratory Intensive Care Unit between June 23, 2020, and October 2, 2020 in University Hospital Center Bezanijska kosa, Belgrade, Serbia.
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Dawei Wang,Bo Hu,Chang Hu,Fangfang Zhu,Xing Liu,Jing Zhang,Binbin Wang,Hui Xiang,Zhenshun Cheng,Yong Xiong,Yan Zhao,Yirong Li,Xinghuan Wang,Zhiyong Peng +13 more
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TL;DR: Hospitalised COVID-19 patients are frequently elderly subjects with co-morbidities receiving polypharmacy, all of which are known risk factors for d
Journal ArticleDOI
Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.
Xiaobo Yang,Yuan Yu,Jiqian Xu,Huaqing Shu,Jia'an Xia,Hong Liu,Hong Liu,Yongran Wu,Lu Zhang,Zhui Yu,Minghao Fang,Ting Yu,Yaxin Wang,Shangwen Pan,Xiaojing Zou,Shiying Yuan,You Shang,You Shang +17 more
TL;DR: The clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia who were admitted to the intensive care unit (ICU) of Wuhan Jin Yin-tan hospital between late December, 2019 and Jan 26, 2020 are described.
Journal ArticleDOI
Incidence of thrombotic complications in critically ill ICU patients with COVID-19.
Frederikus A. Klok,Marieke J. H. A. Kruip,N.J.M. van der Meer,M.S. Arbous,Diederik Gommers,K.M. Kant,F H J Kaptein,J. van Paassen,M A M Stals,Menno V. Huisman,Henrik Endeman +10 more
TL;DR: The findings reinforce the recommendation to strictly apply pharmacological thrombosis prophylaxis in all COVID-19 patients admitted to the ICU, and are strongly suggestive of increasing the prophYLaxis towards high-prophylactic doses, even in the absence of randomized evidence.
Journal ArticleDOI
Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy.
TL;DR: A relatively high mortality of severe coronavirus disease 2019 (COVID‐19) is worrying, and the application of heparin in CO VID‐19 has been recommended by some expert consensus because of the risk of disseminated intravascular coagulation and venous thromboembolism, but its efficacy remains to be validated.