Journal ArticleDOI
Increased risk of cardiovascular disease at suboptimal plasma concentrations of essential antioxidants: an epidemiological update with special attention to carotene and vitamin C.
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TLDR
Previous prudent regimens may now be updated, aiming at an optimal status of all essential and synergistically linked antioxidants, independently of classical IHD risk factors.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 1993-05-01. It has received 298 citations till now. The article focuses on the topics: Vitamin E & Vitamin.read more
Citations
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Journal ArticleDOI
Oxidative Stress and Diabetic Vascular Complications
TL;DR: The suggestion that the different susceptibility of diabetic patients to microvascular and macrovascular complications may be a function of the endogenous antioxidant status is suggested.
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Vitamin C as an Antioxidant: Evaluation of Its Role in Disease Prevention
Sebastian J. Padayatty,Arie Katz,Yaohui Wang,Peter Eck,Oran Kwon,Je-Hyuk Lee,Shenglin Chen,Christopher Corpe,Anand Dutta,Sudhir K. Dutta,Mark Levine +10 more
TL;DR: Dose concentration studies of vitamin C in healthy people showed a sigmoidal relationship between oral dose and plasma and tissue vitamin C concentrations, so optimal dosing is critical to intervention studies using vitamin C.
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Beta-carotene, carotenoids, and disease prevention in humans.
TL;DR: The finding that lung carcinogenesis and cardiovascular disease can be enhanced by sup‐plemental beta‐carotene may ultimately lead to a clearer understanding of the role of diet in the etiology and prevention of these diseases.
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Beta-carotene and other carotenoids as antioxidants.
TL;DR: Epidemiologic studies have shown an inverse relationship between β-carotene and lycopene, which is the most common carotenoid in fruits and vegetables, and the ability to prevent chronic disease.