Journal ArticleDOI
Increased risk of maternal thyroid failure with pregnancy progression in an iodine deficient area with major iodine deficiency disorders.
Francesco Vermiglio,V. Lo Presti,Maria Grazia Castagna,Maria Antonia Violi,Mariacarla Moleti,M. D. Finocchiaro,Filiberto Mattina,A. Artemisia,Francesco Trimarchi +8 more
TLDR
The incidence of isolated hypothyroxinemia or biochemical hypothyroidism doubled between midgestation and term in group A, suggesting that moderate iodine deficiency may result in maternal thyroid failure during the later stages of pregnancy.Abstract:
In an effort to assess the impact of moderate iodine deficiency on maternal thyroid function during pregnancy, we measured serum thyrotropin, total and free thyroid hormones, thyroid-binding globul...read more
Citations
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2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum
Erik K. Alexander,Elizabeth N. Pearce,Gregory A. Brent,Rosalind S. Brown,Herbert Chen,Chrysoula Dosiou,William A. Grobman,Peter Laurberg,John Lazarus,Susan J. Mandel,Robin P. Peeters,Scott Sullivan +11 more
TL;DR: The revised guidelines for the management of thyroid disease in pregnancy include recommendations regarding the interpretation of thyroid function tests in pregnancy, iodine nutrition, thyroid autoantibodies and pregnancy complications, thyroid considerations in infertile women, hypothyroidism in pregnancy and thyrotoxicosis in pregnancy.
Journal ArticleDOI
Management of Thyroid Dysfunction during Pregnancy and Postpartum: An Endocrine Society Clinical Practice Guideline
Leslie J. De Groot,Marcos Abalovich,Erik K. Alexander,Nobuyuki Amino,Linda A. Barbour,Rhoda H. Cobin,Creswell J Eastman,John H. Lazarus,Dominique Luton,Susan J. Mandel,Jorge H. Mestman,Joanne Rovet,Scott Sullivan +12 more
TL;DR: Practice guidelines are presented for diagnosis and treatment of patients with thyroid-related medical issues just before and during pregnancy and in the postpartum interval, including evidence-based approaches to assessing the cause of the condition, treating it, and managing hypothyroidism.
Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and Postpartum The American Thyroid Association Taskforce on Thyroid Disease During Pregnancy and Postpartum
Alex Stagnaro-Green,Marcos Abalovich,Erik K. Alexander,Fereidoun Azizi,Jorge H. Mestman,Roberto Negro,Angelita Nixon,Elizabeth N. Pearce,Offie P. Soldin,Wilmar M. Wiersinga +9 more
TL;DR: Pregnancy is a stress test for the thyroid, resulting in hypothyroidism in women with limited thyroidal reserve or iodine deficiency, and postpartum thyroiditis inWomen with underlying Hashimoto’s disease who were euthyroid prior to conception.
Journal ArticleDOI
Clinical practice guideline: Management of thyroid dysfunction during pregnancy and postpartum: An endocrine society clinical practice guideline
Marcos Abalovich,Nobuyuki Amino,Linda A. Barbour,Rhoda H. Cobin,Leslie J. De Groot,Daniel Glinoer,Susan J. Mandel,Alex Stagnaro-Green +7 more
TL;DR: Management of thyroid diseases during pregnancy requires special considerations because pregnancy induces major changes in thyroid function, and maternal thyroid disease can have adverse effects on the pregnancy and the fetus.
Journal ArticleDOI
2014 European Thyroid Association Guidelines for the Management of Subclinical Hypothyroidism in Pregnancy and in Children
John H. Lazarus,Rosalind S. Brown,Chantal Daumerie,Alicja Hubalewska-Dydejczyk,Roberto Negro,Bijay Vaidya +5 more
TL;DR: This guideline has been produced as the official statement of the European Thyroid Association guideline committee and indicates that targeted antenatal screening for thyroid function will miss a substantial percentage of women with thyroid dysfunction.
References
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Journal ArticleDOI
The Regulation of Thyroid Function in Pregnancy: Pathways of Endocrine Adaptation from Physiology to Pathology
TL;DR: A global view of thyroidal economy in pregnancy and the hypothalamic-pituitary-thyroid axis and the role of hCG are presented.
Journal ArticleDOI
Regulation of Maternal Thyroid during Pregnancy
Daniel Glinoer,P de Nayer,Pierre Bourdoux,Marc Lemone,Claude Robyn,A. Van Steirteghem,Jacques Kinthaert,Bernard Lejeune +7 more
TL;DR: The alterations in maternal thyroid function during gestation are intricate and far from fully understood, and regulation of the maternal thyroid is complex, resulting from both elevated hCG and increasing TSH.
Journal ArticleDOI
Increased need for thyroxine during pregnancy in women with primary hypothyroidism.
TL;DR: The results indicate that the need for thyroxine increases in many women with primary hypothyroidism when they are pregnant, as reflected by an increase in serum thyrotropin concentrations.
Journal ArticleDOI
A randomized trial for the treatment of mild iodine deficiency during pregnancy: maternal and neonatal effects.
Daniel Glinoer,P de Nayer,François Delange,Marc Lemone,Véronique Toppet,M. Spehl,Jean-Paul Grün,Jacques Kinthaert,Bernard Lejeune +8 more
TL;DR: The present work emphasizes the potential risk of goitrogenic stimulation in both mother and newborn in the presence of mild iodine deficiency, and demonstrated that the administration of T4 did not hamper the beneficial effect of iodine supplementation.