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Journal ArticleDOI

Increasing antimicrobial resistance and the management of uncomplicated community-acquired urinary tract infections.

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TLDR
The problem of antimicrobial resistance in acute uncomplicated community-acquired UTI is highlighted, focusing on TMPSMX resistance, and the few available data regarding clinical outcomes associated with in vitro resistance are summarized.
Abstract
The authors highlight the problem of antimicrobial resistance in acute uncomplicated community-acquired urinary tract infection (UTI), summarize the few available data on clinical outcomes associat...

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Citations
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Journal ArticleDOI

Performance of flow cytometry to screen urine for bacteria and white blood cells prior to urine culture

TL;DR: Quantification of bacteria in unspun urine samples by the Sysmex UF-1000i can be used to screen urine samples for those likely to grow >10(5)cfu/mL and in this study population could reduce unnecessary reflex urine cultures by 55%.
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Antibiotic Resistance Pattern of Bacteria Isolated from Patients of Urinary Tract Infections in Iraq

TL;DR: UTI’s in urolithiasis was more frequent in females than males and the percentages were 28/45 and 17/45 respectively and the most effective antimicrobial agent was amikacin and the least effective one was ampicillin.
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A killed, genetically engineered derivative of a wild-type extraintestinal pathogenic E. coli strain is a vaccine candidate.

TL;DR: It is demonstrated that nasal immunization with a formalin-killed ExPEC derivative deficient in capsule and O-antigen results in a significant greater overall humoral response compared to its wild-type derivative and a significantly greater immune response against non-capsular and O -antigen epitopes.
Journal ArticleDOI

Antimicrobials in urogenital infections

TL;DR: The clinical classification in uncomplicated cystitis, uncomPLicated pyelonephritis, complicated UTI and genital infections is useful, also for the right choice of antibiotic treatment, in terms of pharmacokinetic and pharmacodynamic aspects.
Journal ArticleDOI

Sex- and age-specific trends in antibiotic resistance patterns of Escherichia coli urinary isolates from outpatients

TL;DR: Age- and sex-specific trends in antibiotic susceptibility to common urinary anti-infectives among urinary isolates of Escherichia coli from ambulatory primary care patients in a regional health maintenance organization are described.
References
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Book

Principles and Practice of Infectious Diseases

TL;DR: This updated and expanded edition now offers 297 chapters that cover the basic principles of diagnosis and management, major clinical syndromes, all important pathogenic microbes and the diseases they cause, plus a number of specialised topics useful to the practitioner.
Journal ArticleDOI

Guidelines for antimicrobial treatment of uncomplicated acute bacterial cystitis and acute pyelonephritis in women

TL;DR: This guideline is to provide assistance to clinicians in the diagnosis and treatment of two specific types of urinary tract infections (UTIs): uncomplicated, acute, symptomatic bacterial cystitis and acute pyelonephritis in women.
Journal ArticleDOI

Management of urinary tract infections in adults.

TL;DR: This review will highlight recent advances in the treatment of patients in each of these categories, emphasizing cost-effective strategies that may be particularly important in the coming era.
Journal ArticleDOI

Diagnosis and treatment of uncomplicated urinary tract infection

TL;DR: The optimal treatment duration for acute uncomplicated pyelonephritis has not been established, but 10- to 14-day regimens are recommended, and patients prefer to use antimicrobials that attain high renal tissue levels, such as a fluoroquinolone, trimethoprim-sulfamethoxazole, or an aminoglycoside for pyel onephritis.
Journal ArticleDOI

Increasing prevalence of antimicrobial resistance among uropathogens causing acute uncomplicated cystitis in women.

TL;DR: While the prevalence of resistance to trimethoprim-sulfamethoxazole, ampicillin, and cephalothin increased significantly among uropathogens causing acute cystitis, resistance to nitrofurantoin and ciprofloxacin remained infrequent.
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