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Journal ArticleDOI

Increasing antimicrobial resistance and the management of uncomplicated community-acquired urinary tract infections.

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TLDR
The problem of antimicrobial resistance in acute uncomplicated community-acquired UTI is highlighted, focusing on TMPSMX resistance, and the few available data regarding clinical outcomes associated with in vitro resistance are summarized.
Abstract
The authors highlight the problem of antimicrobial resistance in acute uncomplicated community-acquired urinary tract infection (UTI), summarize the few available data on clinical outcomes associat...

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Journal ArticleDOI

Urinary Tract Infections During Pregnancy

TL;DR: Therapeutic management of UTIs in pregnancy requires proper diagnostic workup and thorough understanding of antimicrobial agents to optimize maternal outcome, ensure safety to the fetus, and prevent complications that lead to significant morbidity and mortality in both the fetus and the mother.
Journal ArticleDOI

Antimicrobial susceptibility patterns of community-acquired uropathogens in Tehran, Iran.

TL;DR: Nitrofurantoin may be considered as a first-line empiric antibacterial agent for urinary tract infections in outpatients in Tehran, Iran.
Journal ArticleDOI

Population dynamics and niche distribution of uropathogenic Escherichia coli during acute and chronic urinary tract infection.

TL;DR: It is discovered that each IBC is clonally derived from a single bacterium, and it is argued that during the acute stages of infection, a higher number of IBCs precedes chronic cystitis than precedes QIR formation.
Journal ArticleDOI

Clinical relevance of laboratory-reported antibiotic resistance in acute uncomplicated urinary tract infection in primary care

TL;DR: Empirical antibiotic treatment in acute, uncomplicated UTIs is suggested and trimethoprim resistance was rarer than predicted from routine laboratory submissions and it is calculated that 23 women require microbiological investigation to prevent one reconsultation arising from resistance-based treatment failure.
Journal Article

Containing antibiotic resistance: decreased antibiotic-resistant coliform urinary tract infections with reduction in antibiotic prescribing by general practices

TL;DR: Reducing antibiotic dispensing at general-practice level is associated with reduced local antibiotic resistance, and these findings should further encourage clinicians and patients to use antibiotics conservatively.
References
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Book

Principles and Practice of Infectious Diseases

TL;DR: This updated and expanded edition now offers 297 chapters that cover the basic principles of diagnosis and management, major clinical syndromes, all important pathogenic microbes and the diseases they cause, plus a number of specialised topics useful to the practitioner.
Journal ArticleDOI

Guidelines for antimicrobial treatment of uncomplicated acute bacterial cystitis and acute pyelonephritis in women

TL;DR: This guideline is to provide assistance to clinicians in the diagnosis and treatment of two specific types of urinary tract infections (UTIs): uncomplicated, acute, symptomatic bacterial cystitis and acute pyelonephritis in women.
Journal ArticleDOI

Management of urinary tract infections in adults.

TL;DR: This review will highlight recent advances in the treatment of patients in each of these categories, emphasizing cost-effective strategies that may be particularly important in the coming era.
Journal ArticleDOI

Diagnosis and treatment of uncomplicated urinary tract infection

TL;DR: The optimal treatment duration for acute uncomplicated pyelonephritis has not been established, but 10- to 14-day regimens are recommended, and patients prefer to use antimicrobials that attain high renal tissue levels, such as a fluoroquinolone, trimethoprim-sulfamethoxazole, or an aminoglycoside for pyel onephritis.
Journal ArticleDOI

Increasing prevalence of antimicrobial resistance among uropathogens causing acute uncomplicated cystitis in women.

TL;DR: While the prevalence of resistance to trimethoprim-sulfamethoxazole, ampicillin, and cephalothin increased significantly among uropathogens causing acute cystitis, resistance to nitrofurantoin and ciprofloxacin remained infrequent.
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