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Journal ArticleDOI

Increasing antimicrobial resistance and the management of uncomplicated community-acquired urinary tract infections.

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TLDR
The problem of antimicrobial resistance in acute uncomplicated community-acquired UTI is highlighted, focusing on TMPSMX resistance, and the few available data regarding clinical outcomes associated with in vitro resistance are summarized.
Abstract
The authors highlight the problem of antimicrobial resistance in acute uncomplicated community-acquired urinary tract infection (UTI), summarize the few available data on clinical outcomes associat...

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Journal ArticleDOI

The Risk-based Treatment of Acute Pulmonary Embolism

TL;DR: Modern risk-based therapeutic guidelines of acute PE are focused on, addressing to thrombolysis as treatment choice in selected high risk patients with submassive PE and the indications for unfractioned and low molecular weight heparins and fondaparinux.
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A Recent Study on the Antimicrobial Sensitivity of the Organisms that Cause Urinary Tract Infection

TL;DR: The use of TMP/SMX and nitrofurantoin as the first choices of treatment for UTI should be reconsidered and it is recommended that fluoroquinolone should be restricted because of the high antibiotic resistance and the economic aspects.
Journal ArticleDOI

Molecular evolution of Salmonella enterica serovar Typhimurium and pathogenic Escherichia coli: from pathogenesis to therapeutics.

TL;DR: Virulence factors widely distributed in pathogenic strains, but absent from non-pathogenic bacteria, are interesting targets for the development of novel antimicrobial chemotherapies and vaccines.
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Antimicrobial resistance of Esherichia coli urinary isolates from primary care patients in Greece

TL;DR: A retrospective analysis of microbiological data of the antimicrobial susceptibility of Escherichia coli urinary isolates from primary care patients in Greece offered help to clinicians in deciding the appropriate empirical treatment forPrimary care patients with urinary tract infection and emphasize the increasing problem of antimicrobial resistance even in the primary care setting in Greece.
Journal ArticleDOI

The Importance of Gender-Stratified Antibiotic Resistance Surveillance of Unselected Uropathogens: A Dutch Nationwide Extramural Surveillance Study

TL;DR: Given the observed gender differences in uropathogen distribution and (tendency in) E. coli antibiotic susceptibility, empirical male UTI treatment options should be based on surveillance studies including men only, based on current antibiotic susceptibility data.
References
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Book

Principles and Practice of Infectious Diseases

TL;DR: This updated and expanded edition now offers 297 chapters that cover the basic principles of diagnosis and management, major clinical syndromes, all important pathogenic microbes and the diseases they cause, plus a number of specialised topics useful to the practitioner.
Journal ArticleDOI

Guidelines for antimicrobial treatment of uncomplicated acute bacterial cystitis and acute pyelonephritis in women

TL;DR: This guideline is to provide assistance to clinicians in the diagnosis and treatment of two specific types of urinary tract infections (UTIs): uncomplicated, acute, symptomatic bacterial cystitis and acute pyelonephritis in women.
Journal ArticleDOI

Management of urinary tract infections in adults.

TL;DR: This review will highlight recent advances in the treatment of patients in each of these categories, emphasizing cost-effective strategies that may be particularly important in the coming era.
Journal ArticleDOI

Diagnosis and treatment of uncomplicated urinary tract infection

TL;DR: The optimal treatment duration for acute uncomplicated pyelonephritis has not been established, but 10- to 14-day regimens are recommended, and patients prefer to use antimicrobials that attain high renal tissue levels, such as a fluoroquinolone, trimethoprim-sulfamethoxazole, or an aminoglycoside for pyel onephritis.
Journal ArticleDOI

Increasing prevalence of antimicrobial resistance among uropathogens causing acute uncomplicated cystitis in women.

TL;DR: While the prevalence of resistance to trimethoprim-sulfamethoxazole, ampicillin, and cephalothin increased significantly among uropathogens causing acute cystitis, resistance to nitrofurantoin and ciprofloxacin remained infrequent.
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