Journal ArticleDOI
Increasing antimicrobial resistance and the management of uncomplicated community-acquired urinary tract infections.
Reads0
Chats0
TLDR
The problem of antimicrobial resistance in acute uncomplicated community-acquired UTI is highlighted, focusing on TMPSMX resistance, and the few available data regarding clinical outcomes associated with in vitro resistance are summarized.Abstract:
The authors highlight the problem of antimicrobial resistance in acute uncomplicated community-acquired urinary tract infection (UTI), summarize the few available data on clinical outcomes associat...read more
Citations
More filters
Journal ArticleDOI
Role of Old Antibiotics in the Era of Antibiotic Resistance. Highlighted Nitrofurantoin for the Treatment of Lower Urinary Tract Infections
TL;DR: The mechanism of action, antimicrobial spectrum, pharmacology and safety profile of nitrofurantoin are reviewed, including recent data which highlight its role in the management of community urinary tract infection, especially in cases of multidrug-resistant isolates.
Journal ArticleDOI
Iha from an Escherichia coli Urinary Tract Infection Outbreak Clonal Group A Strain Is Expressed In Vivo in the Mouse Urinary Tract and Functions as a Catecholate Siderophore Receptor
TL;DR: Iha represents a Fur-regulated catecholate siderophore receptor that, uniquely, exhibits an adherence-enhancing phenotype and is the first described urovirulence factor identified in a CGA strain.
Journal Article
Uncomplicated urinary tract infection in women. Current practice and the effect of antibiotic resistance on empiric treatment.
Lindsay E. Nicolle,Peter M. Anderson,John Conly,Thomas C Mainprize,Jamie Meuser,J. Curtis Nickel,Vyta M Senikas,George G. Zhanel +7 more
TL;DR: Trimethoprim-sulfamethoxazole and nitrofurantoin remain first-choice empiric therapy for uUTIs and development of guidelines relevant to family physicians and community education programs that incorporate local susceptibility patterns are important strategies for promoting optimal practice.
Journal ArticleDOI
Pharmacokinetic and pharmacodynamic aspects of antimicrobial agents for the treatment of uncomplicated urinary tract infections.
TL;DR: In vitro time-kill kinetics of fosfomycin against Escherichia coli and Proteus mirabilis showed primarily concentration-dependent activity, with a prolonged post-antibiotic effect, which guarantees optimal efficacy against common uropathogens with an AUC(urine)/MIC ratio of 500.
Journal ArticleDOI
Food safety in the domestic environment
TL;DR: The need to develop some education campaigns designed to educate consumers in good hygiene practices at home is revealed, with handles, knobs and domestic animals' feet being the points more contaminated.
References
More filters
Book
Principles and Practice of Infectious Diseases
TL;DR: This updated and expanded edition now offers 297 chapters that cover the basic principles of diagnosis and management, major clinical syndromes, all important pathogenic microbes and the diseases they cause, plus a number of specialised topics useful to the practitioner.
Journal ArticleDOI
Guidelines for antimicrobial treatment of uncomplicated acute bacterial cystitis and acute pyelonephritis in women
John W. Warren,Elias Abrutyn,J. Richard Hebel,James R. Johnson,Anthony J. Schaeffer,Walter E. Stamm +5 more
TL;DR: This guideline is to provide assistance to clinicians in the diagnosis and treatment of two specific types of urinary tract infections (UTIs): uncomplicated, acute, symptomatic bacterial cystitis and acute pyelonephritis in women.
Journal ArticleDOI
Management of urinary tract infections in adults.
Walter E. Stamm,Thomas M. Hooton +1 more
TL;DR: This review will highlight recent advances in the treatment of patients in each of these categories, emphasizing cost-effective strategies that may be particularly important in the coming era.
Journal ArticleDOI
Diagnosis and treatment of uncomplicated urinary tract infection
Thomas M. Hooton,Walter E. Stamm +1 more
TL;DR: The optimal treatment duration for acute uncomplicated pyelonephritis has not been established, but 10- to 14-day regimens are recommended, and patients prefer to use antimicrobials that attain high renal tissue levels, such as a fluoroquinolone, trimethoprim-sulfamethoxazole, or an aminoglycoside for pyel onephritis.
Journal ArticleDOI
Increasing prevalence of antimicrobial resistance among uropathogens causing acute uncomplicated cystitis in women.
TL;DR: While the prevalence of resistance to trimethoprim-sulfamethoxazole, ampicillin, and cephalothin increased significantly among uropathogens causing acute cystitis, resistance to nitrofurantoin and ciprofloxacin remained infrequent.
Related Papers (5)
Diagnosis and treatment of uncomplicated urinary tract infection
Thomas M. Hooton,Walter E. Stamm +1 more