Infection with high-risk HPV types among female sex workers in northern Vietnam.
Huyen Thi Thanh Hoang,Huyen Thi Thanh Hoang,Huyen Thi Thanh Hoang,Azumi Ishizaki,Cuong Hung Nguyen,Cuong Hung Nguyen,Vuong Thi Tran,Vuong Thi Tran,Kaori Matsushita,Kunikazu Saikawa,Norimitsu Hosaka,Hung Viet Pham,Xiuqiong Bi,Van Thanh Ta,Thuc Van Pham,Hiroshi Ichimura +15 more
TLDR
Results show that HPV‐52 is most prevalent among female sex workers in Northern Vietnam, most of whom had normal cervical cytology, and this information may be important for designing vaccination strategies in Vietnam.Abstract:
Vaccines against two high-risk human papillomavirus (HPV) types, HPV-16, and HPV-18, are in use currently, with high efficacy for preventing infections with these HPV types and consequent cervical cancers. However, circulating HPV types can vary with geography and ethnicity. The aim of this study was to investigate the prevalence of HPV types and the association between HPV types and abnormal cervical cytology among female sex workers in Northern Vietnam. Cervical swabs and plasma samples were collected from 281 female sex workers at two health centers in Hanoi and Hai Phong in 2009. The HPV L1 gene was amplified by PCR using original and modified GP5+/6+ primers. Amplified PCR products were genotyped by the microarray system GeneSquare (KURABO) and/or clonal sequencing. Of the 281 women, 139 (49.5%) were positive for HPV DNA. Among the HPV-positive samples, 339 strains and 29 different types were identified. Multiple-type and high risk-type HPV infections were found in 85 (61.2%) and 124 (89.2%) women, respectively. The most common genotype was HPV-52, followed by HPV-16, HPV-18, and HPV-58. Abnormal cervical cytology was detected in 3.2% (9/281) of the women, and all of these samples were positive for HPV-DNA. Age ≤25 years and infection with human immunodeficiency virus were associated positively with HPV infection among the women while ever smoking was associated negatively. These results show that HPV-52 is most prevalent among female sex workers in Northern Vietnam, most of whom had normal cervical cytology. This information may be important for designing vaccination strategies in Vietnam. J. Med. Virol. 85:288–294, 2013. © 2012 Wiley Periodicals, Inc.read more
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The impact of smoking on HPV infection and the development of anogenital warts
TL;DR: Most current data demonstrate an association between smoking, increased anogenitals HPV infection, and development of anogenital warts, and these data add to the long list of reasons for making smoking cessation a keystone of patient health.
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Characterization of Human Papillomavirus prevalence and risk factors to guide cervical cancer screening in the North Tongu District, Ghana.
Amrei Krings,Priscilla Dunyo,Aleksandra Pesic,Saviour Tetteh,Benjamin T. Hansen,Isaac Gedzah,Comfort Mawusi Wormenor,Joseph E. Amuah,Anna-Lisa Behnke,Daniela Höfler,Michael Pawlita,Andreas M. Kaufmann +11 more
TL;DR: The high risk HPV prevalence detected from this study is higher than estimates reported for Western Africa and needs be considered, when deciding on the cervical cancer screening algorithms introduced on a wider scale.
Journal ArticleDOI
Knowledge and beliefs about HPV among college students in Vietnam and the United States
Akiko Kamimura,Ha Ngoc Trinh,Alla Chernenko,Lindsey Wright,Mary Stoddard,Maziar M. Nourian,Hanh Nguyen +6 more
TL;DR: The increase of knowledge about HPV prevention, including and vaccination, has the potential to be improved through provider interventions and Vietnam could take action toward promoting HPV vaccinations not only at an individual level but also at a national or local level.
Journal ArticleDOI
E6 and E7 Variants of Human Papillomavirus-16 and -52 in Japan, the Philippines, and Vietnam
Azumi Ishizaki,Kaori Matsushita,Huyen Thi Thanh Hoang,Huyen Thi Thanh Hoang,Dorothy M. Agdamag,Cuong Hung Nguyen,Vuong Thi Tran,Toshiyuki Sasagawa,Kunikazu Saikawa,Raphael W. Lihana,Hung Viet Pham,Xiuqiong Bi,Van Thanh Ta,Thuc Van Pham,Hiroshi Ichimura +14 more
TL;DR: Analysis of HPV‐16 and HPV‐52 E6/E7 genes can be a useful molecular‐epidemiological tool to distinguish geographical diffusion routes of these HPV types in Asia.
Journal ArticleDOI
Production of Recombinant Human Papillomavirus Type 52 L1 Protein in Hansenula polymorpha Formed Virus-Like Particles.
TL;DR: This study suggests that the HPV 52 VLPs produced in the methylotrophic yeast Hansenula polymorpha platform may satisfactorily complement available prophylactic vaccines in fighting against HPVs prevalent in Asia.
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