Influenza C virus uses 9-O-acetyl-N-acetylneuraminic acid as a high affinity receptor determinant for attachment to cells.
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TLDR
Investigation of the ability of influenza C virus to agglutinate the erythrocytes of various species correlated with the presence of 9-O-Ac-NeuAc, and the results provide direct evidence that influenza Cirus utilizes 9- O-acetyl-N- acetylneuraminic acid as the primary receptor determinant for attachment to cell surface receptors.About:
This article is published in Journal of Biological Chemistry.The article was published on 1986-05-05 and is currently open access. It has received 291 citations till now. The article focuses on the topics: Influenza C Virus & Influenza A virus.read more
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Membrane-Associated Heparan Sulfate Proteoglycan Is a Receptor for Adeno-Associated Virus Type 2 Virions
TL;DR: It is demonstrated that membrane-associated heparan sulfate proteoglycan serves as the viral receptor for AAV type 2, and an explanation for the broad host range of AAV is provided.
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Chemical Diversity in the Sialic Acids and Related α-Keto Acids: An Evolutionary Perspective
Takashi Angata,Ajit Varki +1 more
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Rescue of Influenza A Virus from Recombinant DNA
Ervin Fodor,Louise J. Devenish,Othmar G. Engelhardt,Peter Palese,George G. Brownlee,Adolfo García-Sastre +5 more
TL;DR: The rescued influenza A virus is rescued by transfection of 12 plasmids into Vero cells by plasmid-based reverse genetics technique, which facilitates the generation of recombinant influenza viruses containing specific mutations in their genes.
Journal ArticleDOI
Sialic Acids as Regulators of Molecular and Cellular Interactions
TL;DR: Sialylation leads to increased anti-inflammatory activity of IgG antibodies, facilitates the escape of microorganisms from the host's immune system, and in polymeric form is involved in the regulation of embryogenesis and neuronal growth and function.
Journal ArticleDOI
Diversity in the sialic acids
TL;DR: This review attempts to briefly summarize current knowledge concerning the occurrence, structure, biochemistry and biological significance of this diversity in the sialic acids.
References
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Book ChapterDOI
Chemistry, Metabolism, and Biological Functions of Sialic Acids
TL;DR: This chapter discusses the chemistry, metabolism, and biological functions of sialic acids and the biosynthesis of N-acetylneuraminic acid is briefly reported and more attention is given to the enzyme reactions modifying this compound.
Journal ArticleDOI
Receptor determinants of human and animal influenza virus isolates: differences in receptor specificity of the H3 hemagglutinin based on species of origin.
Gary Rogers,James C. Paulson +1 more
TL;DR: The binding of influenza virus to erythrocytes and host cells is mediated by the interaction of the viral hemagglutinin with cell surface receptors containing sialic acid, and receptor specificity appeared, to some extent, to be dependent on the species from which the virus was isolated.
Journal ArticleDOI
The Contribution of Sialic Acid to the Surface Charge of the Erythrocyte
Journal ArticleDOI
Structure, biosynthesis and functions of glycoprotein glycans
Eric G. Berger,Eckhart Buddecke,Johannis P. Kamerling,Akira Kobata,James C. Paulson,Johannes F.G. Vliegenthart +5 more
TL;DR: This review may familiarize ‘newcomers’ with the field of glycoconjugate research with special emphasis on glycoprotein glycans and current knowledge on functional roles of glycans is presented.
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Specific gangliosides function as host cell receptors for Sendai virus.
TL;DR: It is demonstrated that gangliosides with the proper carbohydrate sequence, such as GD1a, GT1b, and GQ1B, function as natural receptors for Sendai virus in host cells.