Journal ArticleDOI
Inhibition by Lactoferrin and κ-Casein Glycomacropeptide of Binding of Cholera Toxin to its Receptor
Yoshihiro Kawasaki,Hiroko Isoda,Morimasa Tanimoto,Shun'ichi Dosako,Tadashi Idota,Kenkichi Ahiko +5 more
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TLDR
The competitive binding assay demonstrated that both Lf and GMP inhibited the binding of CT to GM1, although their affinity for CT was lower than that of GM1.Abstract:
Inhibition from binding of Cholera toxin (CT) to Chinese hamster ovary (CHO)-K1 cells and ganglioside GM1 by lactoferrin (Lf) and K-casein glycomacropeptide (GMP) from cow’s milk was examined. Both Lf and GMP effectively reduced the CT-derived morphological changes in CHO-K1 cells. The competitive binding assay demonstrated that both Lf and GMP inhibited the binding of CT to GMH although their affinity for CT was lower than that of GM1. The inhibitory effect of Lf and GMP seemed to be attributed to their terminal sialic acid, although the sugar chain sequence only partially fitted to the CT-receptor.read more
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Bovine whey proteins – Overview on their main biological properties
Ana Raquel Madureira,Cláudia I. Pereira,Ana M. P. Gomes,Maria Manuela Pintado,F. Xavier Malcata +4 more
TL;DR: The most important advances reported to date pertaining to biological properties of whey proteins are reviewed in this communication.
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Bioactive Properties of Milk Proteins with Particular Focus on Anticariogenesis
TL;DR: Beyond nutrition, there is an increasing amount of data and information to demonstrate a bioactive role for dairy components in adults including a role in prevention of dental caries, and the casein fraction and hydrolysates thereof have been the focus of researchers investigating cariogenicity prevention.
Journal ArticleDOI
Biological activities of bovine glycomacropeptide.
TL;DR: Protection against toxins, bacteria, and viruses and modulation of the immune system are the most promising applications of GMP.
Journal ArticleDOI
Casein-derived bioactive peptides: biological effects, industrial uses, safety aspects and regulatory status.
TL;DR: A review of casein-derived bioactive peptides, their application in industry, in addition to safety aspects and regulations relating to the use of these peptides can be found in this article.
Journal ArticleDOI
Invited review: Physiological properties of bioactive peptides obtained from whey proteins
Ana Raquel Madureira,Tânia G. Tavares,Ana M. P. Gomes,Maria Manuela Pintado,Francisco Xavier Malcata +4 more
TL;DR: The specific physiological effects, as well the mechanisms by which they are achieved and the stabilities of the peptides obtained from various whey fractions during their gastrointestinal route are specifically discussed in this review.
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Variations and Distributions of O-Glycosidically Linked Sugar Chains in Bovine κ-Casein
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