Journal ArticleDOI
Inhibitory effects on serum and pituitary LH by a melatonin-free extract of bovine pineal glands
Richard J. Orts,Bryant Benson +1 more
TLDR
An aqueous extract of bovine pineal glands, partially purified by chromatography and ultrafiltration to exclude melatonin, was tested for it's ability to inhibit serum and pituitary LH in orchidectomized rats and significantly inhibited the 24 and 96 hour post-castration rise of serum LH.About:
This article is published in Life Sciences.The article was published on 1973-06-08. It has received 34 citations till now. The article focuses on the topics: Ultrafiltration & Melatonin.read more
Citations
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Journal ArticleDOI
Immunohistological localization of N-acetylindolealkylamines in pineal gland, retina and cerebellum
TL;DR: Staining by a double antibody technique using fluorescein or peroxidase labeling revealed that N-acetylindole is present not only in the parenchymal cells of the pineal gland but also in the outer nuclear layer of the retina and in the granule and Golgi II cells of cerebellum.
Journal ArticleDOI
Melatonin, the pineal gland and their implications for headache disorders.
TL;DR: A doubleblind, placebo-controlled trial shows melatonin is effective in cluster headache prevention, other studies also show benefit in other disorders and new avenues for studying their pathophysiology and treatment are offered.
Journal ArticleDOI
Potential therapeutic use of melatonin in migraine and other headache disorders.
Mario Fernando Prieto Peres,Marcelo Rodrigues Masruha,Eliova Zukerman,Carlos Alberto Moreira-Filho,Esper A. Cavalheiro +4 more
TL;DR: The treatment of headache disorders with melatonin and other chronobiotic agents, such as melatonin agonists (ramelteon and agomelatin), is promising and there is a great potential for their use in headache treatment.
Book
Neurosecretion - The Final Neuroendocrine Pathway
Francis Knowles,Lutz Vollrath +1 more
TL;DR: The results of these studies suggest that the habenulo-epiphysial system may constitute an important neuroendocrine component in the regulation of menstrual cycles in response to circulating levels of gonadal hormones.
Journal ArticleDOI
Termination of photorefractoriness in golden hamsters-photoperiodic requirements.
TL;DR: The data show that hamsters begin measuring long days to terminate photorefractoriness irrespective of the physiological state of the reproductive system, and, therefore, that photoreFractoriness is induced some time during the period of testicular regression (during the first 10-12 weeks of short day exposure).
References
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Journal ArticleDOI
Melatonin, a pineal substance: effect on the rat ovary.
TL;DR: Daily injection of microgram amounts of melatonin in rats decreased the incidence of estrus and reduced ovarian weight and Circulating melatonin was selectively taken up and retained by the ovary and pineal gland.
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Effects of pinealectomy and of a bovine pineal extract in rats.
TL;DR: Giving the extract of a protein-free bovine pineal extract to intact animals caused effects varying with the dose, which reversed changes in ovarian hypertrophy, pituitary hyperTrophy, and adrenalhypertrophy.
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Analysis of initial and delayed effects of orchidectomy and ovariectomy on pituitary and serum LH levels in adult and immature rats.
TL;DR: Although serum LH levels did not match those of comparable males during the first 10 post-castration days, they did reach or surpass them later; the pattern of pituitary LH changes also differed: in males, LH stores initially fell, reaching a nadir at about day 4; females exhibited no such fall.
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Brain receptors sensitive to indole compounds: function in control of luteinizing hormone secretion.
TL;DR: It is suggested that these indole compounds, which are normally synthesized in the pineal gland, may intervene in the control of the secretion of luteinizing hormone, possibly by acting on specific receptors localized in the median eminence and in the midbrain.
Journal ArticleDOI
Evidence for the Presence of Lysine Vasotocin in the Pig Pineal Gland
TL;DR: A peptide with pressor, antidiuretic, rat and hen oxytocic, and frog bladder activities has been identified in an extract of pig pineal glands, which is not significantly different from those of synthetic lysine vasotocin.