Journal ArticleDOI
Localization of a sheep pineal antigonadotropin
I. Ebels,B. Benson,M.J. Matthews +2 more
TLDR
When injected into male and female Charles River CD-1 albino mice the low molecular weight fractions from Sephadex G-25, and after ultrafiltration the UM-05 residue of these fractions, demonstrated significant effects on the reproductive system.About:
This article is published in Analytical Biochemistry.The article was published on 1973-12-01. It has received 50 citations till now. The article focuses on the topics: Sephadex.read more
Citations
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Journal ArticleDOI
Melatonin as an antioxidant: under promises but over delivers.
Russel J. Reiter,Juan C. Mayo,Dun Xian Tan,Rosa M. Sainz,Moisés Alejandro Alatorre-Jiménez,Lilian Qin +5 more
TL;DR: It is the current feeling of the authors that, in view of the widely diverse beneficial functions that have been reported for melatonin, these may be merely epiphenomena of the more fundamental, yet‐to‐be identified basic action(s) of this ancient molecule.
Journal Article
Effect of Melatonin on Mammary Carcinogenesis in Intact and Pinealectomized Rats in Varying Photoperiods
TL;DR: It is concluded that, to have an impressive antitumor effect, presence of the pineal gland is essential, and the probable site of melatonin action appears to be at both the Pineal gland and the hypothalamus.
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Melatonin: Antigonadal and progonadal effects in male golden hamsters
TL;DR: The results demonstrate that melatonin can exert either pro- or antigonadal effects and emphasize that the effects ofmelatonin on the testis cannot be properly assessed unless account is taken of the dosage and mode of melatonin administration and the photoperiod on which experimental animals are maintained.
Journal ArticleDOI
Melatonin: Its Inhibition of Pineal Antigonadotrophic Activity in Male Hamsters
TL;DR: The results suggest that melatonin is not the pineal antigonadotrophic factor in the male golden hamster and that pituitary levels of prolactin return to normal after pinealectomy and melatonin treatment.
References
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Journal ArticleDOI
Melatonin, a pineal substance: effect on the rat ovary.
TL;DR: Daily injection of microgram amounts of melatonin in rats decreased the incidence of estrus and reduced ovarian weight and Circulating melatonin was selectively taken up and retained by the ovary and pineal gland.
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Endocrine aspects of the mammalian pineal gland: a review.
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5-Methoxytryptophol: Effect on Estrus and Ovarian Weight
TL;DR: Daily injection of 5-methoxytryptophol in microgram quantities in rats decreased the incidence of estrus and reduced ovarian weight in maturing animals.