Journal ArticleDOI
Interaction of factors determining oxygen uptake at the onset of exercise.
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TLDR
A review of biochemical evidence suggests that a given respiratory rate is a function of the net drive of phosphorylation potential and redox potential and cellular mitochondrial PO2 (PmitoO2), which appears to be within a range capable of modulating muscle metabolism.Abstract:
Considerable debate surrounds the issue of whether the rate of adaptation of skeletal muscle O2 consumption (Q˙o 2) at the onset of exercise is limited by1) the inertia of intrinsic cellular metabo...read more
Citations
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Journal ArticleDOI
Influence of exercise intensity on the on- and off-transient kinetics of pulmonary oxygen uptake in humans
TL;DR: The kinetics of V̇O2 during dynamic muscular exercise are strikingly influenced by the exercise intensity, both with respect to model order and to dynamic asymmetries between the on‐ and off‐transient responses.
Journal ArticleDOI
Muscle oxygenation and pulmonary gas exchange kinetics during cycling exercise on-transitions in humans
Bruno Grassi,Silvia Pogliaghi,Susanna Rampichini,Valentina Quaresima,Marco Ferrari,Claudio Marconi,Paolo Cerretelli +6 more
TL;DR: The constant muscle oxygenation during the initial phase of the on-transition indicates a tight coupling between increases in O2 delivery and O2 utilization and adequacy of O2 availability in relation to needs.
OtherDOI
Oxygen Uptake Kinetics
David C. Poole,Andrew M. Jones +1 more
TL;DR: Greater understanding of VO2 kinetics control and, in particular, its relation to the plasticity of the O2-transport/utilization system is considered important for improving the human condition, not just in athletic populations, but crucially for patients suffering from pathologically slowed VO2Kinetics as well as the burgeoning elderly population.
Journal ArticleDOI
Oxygen uptake kinetics as a determinant of sports performance
Mark Burnley,Andrew M. Jones +1 more
TL;DR: In this article, the authors explore the basis for these relationships by explaining the influence of these “traditional” variables on the dynamic profiles of the response to exercise of different intensities, and how these differences in dynamics are related to exercise tolerance and fatigue.
Journal ArticleDOI
Effects of prior heavy exercise on phase II pulmonary oxygen uptake kinetics during heavy exercise
TL;DR: Neither moderate- nor heavy-intensity exercise had an effect on the VO(2) kinetic response to subsequent moderate exercise, suggesting phase II VO( 2) kinetics are not speeded by prior heavy exercise.
References
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Journal ArticleDOI
Handbook of Physiology.
TL;DR: This is the first volume of the proposed many-sectioned "Handbook" in which the American Physiological Society intends to present comprehensively the entire field of physiology.
Book ChapterDOI
The respiratory chain and oxidative phosphorylation.
Britton Chance,G. R. Williams +1 more
TL;DR: How the respiratory chain and oxidative phosphorylation works and which substances may disable it are explained.
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Exercise : regulation and integration of multiple systems
TL;DR: This paper presents a meta-analyses of the cellular, molecular and Metabolic Basis of Muscle Fatigue, and discusses the role of Exercise in the development of Neural Control of Movement.
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Biochemistry for the Medical Sciences
Eric A. Newsholme,A. R. Leech +1 more
TL;DR: This outstanding text, written in a clear, concise and easy-to-read style, provides students with an in-depth explanation of how each metabolic pathway is directly related to physiology, pharmacology, and clinical medicine.