Journal ArticleDOI
Intracranial Gadolinium Deposition after Contrast-enhanced MR Imaging.
Robert J. McDonald,Jennifer S. McDonald,David F. Kallmes,Mark E. Jentoft,David L. Murray,Kent R. Thielen,Eric E. Williamson,Laurence J. Eckel +7 more
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TLDR
Intravenous GBCA exposure is associated with neuronal tissue deposition in the setting of relatively normal renal function and the generalizability to other GBCAs is investigated.Abstract:
Intravenous administration of gadolinium-based contrast material is associated with dose-dependent deposition in neuronal tissues that is unrelated to renal function, age, or time between exposure and death.read more
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Rare earth elements:A review of applications, occurrence, exploration, analysis, recycling, and environmental impact
TL;DR: In this article, the authors summarized the occurrence of rare earth elements in the Earth's crust, their mineralogy, different types of deposits both on land and oceans from the standpoint of the new data with more examples from the Indian subcontinent.
Journal ArticleDOI
Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications.
Seyed Mohammadali Dadfar,Karolin Roemhild,Natascha Drude,Saskia von Stillfried,Ruth Knüchel,Fabian Kiessling,Twan Lammers,Twan Lammers,Twan Lammers +8 more
TL;DR: The synthesis, surface functionalization and characterization of iron oxide nanoparticles, as well as their (pre‐) clinical use in diagnostic, therapeutic and theranostic settings, are summarized.
Journal ArticleDOI
Gadolinium deposition in the brain: summary of evidence and recommendations
Vikas Gulani,Fernando Calamante,Fernando Calamante,Frank G. Shellock,Emanuel Kanal,Scott B. Reeder +5 more
TL;DR: Recommendations for the clinical and research use of gadolinium-based contrast agents are presented and might evolve as new evidence becomes available.
Journal ArticleDOI
Gadolinium Retention in the Dentate Nucleus and Globus Pallidus Is Dependent on the Class of Contrast Agent
Alexander Radbruch,Lukas D. Weberling,Pascal J. Kieslich,Oliver Eidel,Sina Burth,Philipp Kickingereder,Sabine Heiland,Wolfgang Wick,Heinz Peter Schlemmer,Martin Bendszus +9 more
TL;DR: This study indicates that an SI increase in the DN and GP on T1-weighted images is caused by serial application of the linear GBCA gadopentetate dimeglumine but not by the macrocyclic GBCAs gadoterate meglumines.
Journal ArticleDOI
Exceedingly small iron oxide nanoparticles as positive MRI contrast agents
He Wei,Oliver T. Bruns,Michael G. Kaul,E. V. Hansen,Mariya Barch,Agata Wiśniowska,Ou Chen,Yue Chen,Nan Li,Satoshi Okada,Jose M. Cordero,Markus Heine,Christian T. Farrar,Daniel M. Montana,Gerhard Adam,Harald Ittrich,Alan Jasanoff,Peter Nielsen,Moungi G. Bawendi +18 more
TL;DR: Zwitterion-coated exceedingly small superparamagnetic iron oxide nanoparticles (ZES-SPIONs) as discussed by the authors are free of Gd and show a high T1 contrast power.
References
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Journal ArticleDOI
A more accurate method to estimate glomerular filtration rate from serum creatinine: A new prediction equation
TL;DR: The purpose of this study was to develop an equation from MDRD Study data that could improve the prediction of GFR from serum creatinine concentration, and major clinical decisions in general medicine, geriatrics, and oncology are made by using the Cockcroft-Gault formula and other formulas to predict the level of renal function.
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Gadolinium(III) Chelates as MRI Contrast Agents: Structure, Dynamics, and Applications
TL;DR: A. Relaxivity 2331 E. Outerand Second-Sphere relaxivity 2334 F. Methods of Improving Relaxivity 2336 V. Macromolecular Conjugates 2336.
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Gadolinium—a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis?
TL;DR: Nine end stage renal disease patients undergoing magnetic resonance (MR) angiography are presented, in five of whom skin changes of nephrogenic fibrosing dermatopathy became apparent about 2–4 weeks after the administration of gadolinium-containing contrast agent for MR, demonstrating that Gd–DTPA possibly plays a triggering role in the development of NFD under certain circumstances.
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High Signal Intensity in the Dentate Nucleus and Globus Pallidus on Unenhanced T1-weighted MR Images: Relationship with Increasing Cumulative Dose of a Gadolinium-based Contrast Material
TL;DR: High SI in the dentate nucleus and globus pallidus on unenhanced T1-weighted magnetic resonance (MR) images may be a consequence of the number of previous gadolinium-based contrast material administrations.