Proceedings ArticleDOI
Investigation of viscoelastic properties of human liver tissue using MR elastography and FE modeling
Mohammad Haghpanahi,Hamed Ajabi Naeeni +1 more
- pp 1-4
TLDR
Focusing on the dynamic behavior of shear storage and loss moduli obtained by MRE at different frequency ranges resulted in a viscoelastic FE model of liver tissue that validated the finite element as an effective technique for measurement of rheologic material properties.Abstract:
Viscoelasticity is an inherent property of the soft biological tissue and is increasingly used as a diagnostic parameter, e.g. in characterizing liver fibrosis and breast tumors or tissue-mimicking phantoms preparation. MR elastography (MRE) enables the noninvasive determination of the viscoelastic behavior of human internal organs. In this study, multifrequency magnetic resonance elastography was used to investigate and validate the numerical simulation of liver viscoelastic phantom generated by ABAQUS. The dynamic behavior of shear storage (G′) and loss moduli (G″) obtained by MRE at different frequency ranges were used to generate viscoelastic FE model of liver tissue. Then, shear modulus(μ) and shear viscosity(η) were compared to other experimental data. MRE validate the finite element as an effective technique for measurement of rheologic material properties.read more
Citations
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Journal ArticleDOI
Sample, testing and analysis variables affecting liver mechanical properties: A review.
Giorgio Mattei,Arti Ahluwalia +1 more
TL;DR: This review identifies and discusses sample and testing variables which can influence the mechanical behaviour of hepatic tissue and consequently the measured mechanical properties and establishes new testing methods and experimental recommendations for sample preparation and testing.
Journal ArticleDOI
Viscoelastic characterisation of pig liver in unconfined compression.
TL;DR: This approach, termed step-reconstructed DMA (SRDMA), is based on dynamic measurements around specific frequencies and then reconstruction of liver behaviour in the entire frequency range of interest, which shows that the overestimation of stiffness is due to data acquisition in a local rather than an absolute LVR.
Journal ArticleDOI
Analysis of liver viscosity behavior as a function of multifrequency magnetic resonance elastography (MMRE) postprocessing
Gwladys E. Leclerc,Fabrice Charleux,Ludovic Robert,Marie-Christine Ho Ba Tho,Colette Rhein,Jean-Paul Latrive,Sabine F. Bensamoun +6 more
TL;DR: To analyze the relevance of the viscosity measurement as a liver diagnostic marker, a large number of studies have used it as a biomarker for liver cancer diagnosis.
Journal ArticleDOI
A Model of Interfacial Permeability for Soft Seals in Marine-Organism, Suction-Based Adhesion
TL;DR: In this paper, a theoretical framework based on measurable structural, material, and topological properties is developed to better understand a critical aspect of suction-based attachment strategies: the leakage rate.
Journal ArticleDOI
A New Hybrid Viscoelastic Soft Tissue Model based on Meshless Method for Haptic Surgical Simulation
TL;DR: Simulated results show that TPM has better real-time, stability and accuracy, and also has better stress-strain, stress relaxation and creep properties.
References
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Journal ArticleDOI
Magnetic resonance elastography by direct visualization of propagating acoustic strain waves
Raja Muthupillai,D. J. Lomas,Phillip J. Rossman,James F. Greenleaf,Armando Manduca,Richard L. Ehman +5 more
TL;DR: The results indicate that displacement patterns corresponding to cyclic displacements smaller than 200 nanometers can be measured and suggest the feasibility of a medical imaging technique for delineating elasticity and other mechanical properties of tissue.
Journal ArticleDOI
Magnetic resonance elastography: Non-invasive mapping of tissue elasticity
Armando Manduca,Travis E. Oliphant,M. A. Dresner,J. L. Mahowald,Scott A. Kruse,E. Amromin,Joel P. Felmlee,James F. Greenleaf,Richard L. Ehman +8 more
TL;DR: Magnetic resonance elastography shows promise as a potential technique for 'palpation by imaging', with possible applications in tumor detection, characterization of disease, and assessment of rehabilitation (particularly in muscle).
Journal ArticleDOI
Viscoelastic shear properties of in vivo breast lesions measured by MR elastography
TL;DR: The in vivo results show a good separation between breast cancer and benign fibroadenoma utilizing the shear modulus and the results as obtained for theShear viscosity do not indicate to be useful for separating benign from malignant lesions.
Journal ArticleDOI
Noninvasive assessment of the rheological behavior of human organs using multifrequency MR elastography: a study of brain and liver viscoelasticity.
TL;DR: An experiment was developed that combines multifrequency shear wave actuation with broad-band motion sensitization to extend the dynamic range of a single MRE examination, indicating that human brain is softer and possesses a higher viscosity than liver.