Is There “One” DLPFC in Cognitive Action Control? Evidence for Heterogeneity From Co-Activation-Based Parcellation
Edna C. Cieslik,Karl Zilles,Svenja Caspers,Christian Roski,Tanja S. Kellermann,Tanja S. Kellermann,Oliver Jakobs,Oliver Jakobs,Robert Langner,Robert Langner,Angela R. Laird,Peter T. Fox,Simon B. Eickhoff +12 more
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TLDR
Evidence is provided that cognitive action control in the right DLPFC may rely on differentiable neural networks and cognitive functions, as well as task-dependent and task-independent connectivity, which revealed both clusters to be involved in distinct neural networks.Abstract:
The dorsolateral prefrontal cortex (DLPFC) has consistently been implicated in cognitive control of motor behavior. There is, however, considerable variability in the exact location and extension of these activations across functional magnetic resonance imaging (fMRI) experiments. This poses the question of whether this variability reflects sampling error and spatial uncertainty in fMRI experiments or structural and functional heterogeneity of this region. This study shows that the right DLPFC as observed in 4 different experiments tapping executive action control may be subdivided into 2 distinct subregions-an anterior-ventral and a posterior-dorsal one - based on their whole-brain co-activation patterns across neuroimaging studies. Investigation of task-dependent and task-independent connectivity revealed both clusters to be involved in distinct neural networks. The posterior subregion showed increased connectivity with bilateral intraparietal sulci, whereas the anterior subregion showed increased connectivity with the anterior cingulate cortex. Functional characterization with quantitative forward and reverse inferences revealed the anterior network to be more strongly associated with attention and action inhibition processes, whereas the posterior network was more strongly related to action execution and working memory. The present data provide evidence that cognitive action control in the right DLPFC may rely on differentiable neural networks and cognitive functions.read more
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Functional Spectroscopy Mapping of Pain Processing Cortical Areas During Non-painful Peripheral Electrical Stimulation of the Accessory Spinal Nerve.
Janete Shatkoski Bandeira,Luciana da Conceição Antunes,Matheus Dorigatti Soldatelli,João Ricardo Sato,Felipe Fregni,Wolnei Caumo +5 more
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Aging and response conflict solution: behavioural and functional connectivity changes
Robert Langner,Robert Langner,Edna C. Cieslik,Edna C. Cieslik,Simone D. Behrwind,Christian Roski,Svenja Caspers,Katrin Amunts,Katrin Amunts,Simon B. Eickhoff,Simon B. Eickhoff +10 more
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Altered resting state functional connectivity of the cognitive control network in fibromyalgia and the modulation effect of mind-body intervention
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Blue-Light Therapy following Mild Traumatic Brain Injury: Effects on White Matter Water Diffusion in the Brain
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Prefrontal control and predictors of cognitive behavioral therapy response in social anxiety disorder
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