Journal ArticleDOI
Kefir improves the efficacy and tolerability of triple therapy in eradicating Helicobacter pylori.
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TLDR
It is concluded that a 14-day regimen of triple therapy with kefir is more effective in achieving H. pylori eradication than is triple therapy alone.Abstract:
Preliminary evidence has suggested that probiotics may improve eradication rates in patients infected with Helicobacter pylori treated by triple therapy. This study examined the effect of combining triple therapy with kefir, a fermented milk drink containing probiotics. A randomized, double-blind study was carried out on 82 consecutive patients with symptoms of dyspepsia and H. pylori infection confirmed by the urea breath test. Patients were given a two times a day, 14-day course of lansoprazole (30 mg), amoxicillin (1,000 mg), and clarithromycin (500 mg) with either 250 mL of kefir twice daily (triple therapy + kefir, n = 46) or 250 mL of milk containing placebo (triple therapy + placebo, n = 36). Side effects were determined using a standard questionnaire form at 15 days after beginning treatment. Patients returned for urea breath tests 45 days after beginning treatment. Significantly more triple therapy + kefir patients achieved eradication (36 of 46 [78.2%]) compared with triple therapy + pl...read more
Citations
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Journal ArticleDOI
Probiotics for the prevention of Clostridium difficile‐associated diarrhea in adults and children
Joshua Z. Goldenberg,Christina Yap,Lyubov Lytvyn,Calvin Ka-Fung Lo,Jennifer Beardsley,Dominik Mertz,Bradley C. Johnston +6 more
TL;DR: The overall evidence warrants moderate confidence in this large relative risk reduction of C. difficile infection in adults and children, and the overall quality of evidence for CDAD is downgraded to 'moderate' due to imprecision.
Journal ArticleDOI
Fermented Foods: Definitions and Characteristics, Impact on the Gut Microbiota and Effects on Gastrointestinal Health and Disease
TL;DR: There is very limited clinical evidence for the effectiveness of most fermented foods in gastrointestinal health and disease and clinical high-quality trials investigating the health benefits of fermented foods are warranted.
Journal ArticleDOI
Milk kefir: nutritional, microbiological and health benefits.
Damiana Diniz Rosa,Manoela Maciel dos Santos Dias,Łukasz Grześkowiak,Sandra Aparecida dos Reis,Lisiane Lopes da Conceição,Maria do Carmo Gouveia Peluzio +5 more
TL;DR: There is a need for systematic clinical trials to better understand the effects of regular use of kefir as part of a diet, and for their effect on preventing diseases.
Journal ArticleDOI
پروبیوتیکها برای پیشگیری از اسهال ناشی از کلستریدیوم دیفیسیل (Clostridium difficile) در بزرگسالان و کودکان
Journal ArticleDOI
The effect of probiotics supplementation on Helicobacter pylori eradication rates and side effects during eradication therapy: a meta-analysis.
TL;DR: The pooled data suggest that supplementation with specific strains of probiotics compared with eradication therapy may be considered an option for increasing eradication rates, particularly when antibiotic therapies are relatively ineffective.
References
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Journal ArticleDOI
Report of the 1997 Asia Pacific consensus conference on the management of Helicobacter pylori infection
S. K. Lam,Nicholas J. Talley +1 more
TL;DR: While evidence is inconclusive to support treatment of H. pylori infection in non‐ulcer dyspepsia, it was agreed that treatment be offered to patients with documented infection on a case‐by‐case basis.
Journal ArticleDOI
Effect of different probiotic preparations on anti-Helicobacter pylori therapy-related side effects: a parallel group, triple blind, placebo-controlled study
Filippo Cremonini,Simona Di Caro,Marcello Covino,Alessandro Armuzzi,Maurizio Gabrielli,Luca Santarelli,Enrico Celestino Nista,Giovanni Cammarota,Giovanni Gasbarrini,Antonio Gasbarrini +9 more
TL;DR: All the probiotics used were superior to placebo for side effect prevention, but were not associated with better compliance with antibiotic therapy.
Journal ArticleDOI
New concepts of resistance in the treatment of Helicobacter pylori infections.
David Y. Graham,Akiko Shiotani +1 more
TL;DR: This Review discusses concepts of resistance that have become part of mainstream thinking for other infectious diseases but have not yet become so with regard to H. pylori and attempts to anticipate the direction that research will take to provide clinicians with reliable approaches to this serious infection.
Journal ArticleDOI
The effect of oral administration of Lactobacillus GG on antibiotic‐associated gastrointestinal side‐effects during Helicobacter pylori eradication therapy
Alessandro Armuzzi,Filippo Cremonini,F. Bartolozzi,Filippo Canducci,Marcello Candelli,Veronica Ojetti,Giovanni Cammarota,Marcello Anti,A De Lorenzo,Paolo Pola,Giovanni Gasbarrini,Antonio Gasbarrini +11 more
TL;DR: One‐week triple therapy is currently considered the golden standard against Helicobacter pylori, however, gastrointestinal side‐effects are among the major pitfalls in such regimens and probiotic supplementation might help to prevent or reduce such drug‐related manifestations.
Journal ArticleDOI
Meta-analysis: the effect of supplementation with probiotics on eradication rates and adverse events during Helicobacter pylori eradication therapy.
TL;DR: Recent evidence found probiotics could inhibit Helicobacter pylori colonization from both in vitro and in vivo studies.