Journal ArticleDOI
Lanthanide triflate catalyzed Biginelli reaction. one-pot synthesis of dihydropyrimidinones under solvent-free conditions.
About:
This article is published in Journal of Organic Chemistry.The article was published on 2000-05-18. It has received 460 citations till now. The article focuses on the topics: Biginelli reaction & Trifluoromethanesulfonate.read more
Citations
More filters
Journal ArticleDOI
Rare-earth metal triflates in organic synthesis
TL;DR: The main findings are: Lanthanide(II) Triflates in Organic Synthesis inorganic Synthesis 2295 10.2.1.
Journal ArticleDOI
Solvent-free heterocyclic synthesis.
TL;DR: 1. Six-Membered Heterocycles with One Heteroatom 4155 7.6.1.
Journal ArticleDOI
Utilisation of 1,3‐Dicarbonyl Derivatives in Multicomponent Reactions
TL;DR: In this article, an overview of the potential of 1,3-dicarbonyl derivatives for the selective construction of highly functionalised small organic molecules of high synthetic and biological value is presented.
Journal ArticleDOI
Recent advances in multicomponent reactions for diversity-oriented synthesis
TL;DR: This review will highlight recent developments in MCRs as a rich source of molecular diversity as well as the discovery of new reactions, development of the first asymmetric catalysts, and the application of M CRs to natural products and other targets of biological interest.
Journal ArticleDOI
Recent developments in solvent-free multicomponent reactions: a perfect synergy for eco-compatible organic synthesis
TL;DR: In this paper, the authors summarized the results reported mainly within the last 10 years, and it is quite clear from the growing number of emerging publications in this field that the possibility to utilize multicomponent technology allows reaction conditions to be accessed that are very valuable for organic synthesis.
References
More filters
Journal ArticleDOI
Dihydropyrimidine calcium channel blockers. 3. 3-Carbamoyl-4-aryl-1,2,3,4-tetrahydro-6-methyl-5-pyrimidinecarboxylic acid esters as orally effective antihypertensive agents.
Karnail Atwal,Brian N. Swanson,Steven E. Unger,Floyd David M,Suzanne Moreland,Anders Hedberg,Brian C. O'Reilly +6 more
TL;DR: The results demonstrate that the active R-(-)-enantiomer 20a of 7 is both more potent and longer acting than nifedipine (1) as an antihypertensive agent in the SHR.
Journal ArticleDOI
Novel Alkaloids from the Sponge Batzella sp.: Inhibitors of HIV gp120-Human CD4 Binding
Ashok D. Patil,N. Vasant Kumar,W. C. M. C. Kokke,Mark F. Bean,Alan J. Freyer,Charles De Brosse,Shing Mai,Alemseged Truneh,Brad Carte +8 more
Journal ArticleDOI
Unprecedented Catalytic Three Component One-Pot Condensation Reaction: An Efficient Synthesis of 5-Alkoxycarbonyl- 4-aryl-3,4-dihydropyrimidin-2(1H)-ones
TL;DR: Biginelli's initial one-pot reflux of â-keto ester 2, aryl aldehyde 3, and urea, 4, with catalytic acid in a protic solvent frequently afforded low (20-50%) yields as mentioned in this paper.
Journal ArticleDOI
Substituted 1,4-dihydropyrimidines. 3. Synthesis of selectively functionalized 2-hetero-1,4-dihydropyrimidines
TL;DR: Par reactions electrophiles selectives sur les [p-anisilyloxy-2- ou p -anisylthio-2 dihydro-1,4 nitro-3'phenyl-4 methyl-6] pyrimidinecarboxylates-5 d'ethyle.