Journal ArticleDOI
Longitudinal Alveolar Bone Loss in Postmenopausal Osteoporotic/Osteopenic Women
TLDR
The data suggest that osteoporosis/osteopenia and estrogen deficiency are risk factors for alveolar bone density loss in postmenopausal women with a history of periodontitis.Abstract:
The purpose of this 2-year longitudinal clinical study was to investigate alveolar (oral) bone height and density changes in osteoporotic/osteopenic women compared with women with normal lumbar spine bone mineral density (BMD) Thirty-eight postmenopausal women completed this study; 21 women had normal BMD of the lumbar spine, while 17 women had osteoporosis or osteopenia of the lumbar spine at baseline All subjects had a history of periodontitis and participated in 3- to 4-month periodontal maintenance programs No subjects were current smokers All patients were within 5 years of menopause at the start of the study Four vertical bitewing radiographs of posterior sextants were taken at baseline and 2-year visits Radiographs were examined using computer-assisted densitometric image analysis (CADIA) for changes in bone density at the crestal and subcrestal regions of interproximal bone Changes in alveolar bone height were also measured Radiographic data were analyzed by the t-test for two independent samples Osteoporotic/osteopenic women exhibited a higher frequency of alveolar bone height loss (p<005) and crestal (p<0025) and subcrestal (p<003) density loss relative to women with normal BMD Estrogen deficiency was associated with increased frequency of alveolar bone crestal density loss in the osteoporotic/osteopenic women and in the overall study population (p<005) These data suggest that osteoporosis/osteopenia and estrogen deficiency are risk factors for alveolar bone density loss in postmenopausal women with a history of periodontitisread more
Citations
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Periodontal Conditions in Elderly Men With and Without Osteoporosis or
Osteopenia Shum,Ping-Chung Leung,Anthony W.L. Kwok,Esmonde F. Corbet,Eric S. Orwoll,Lijian Jin +5 more
TL;DR: Osteoporosis remained significantly associated with severe clinical AL and interproximal GR after adjusting for age, supragingival plaque, and number of teeth lost in elderly Chinese men.
Journal ArticleDOI
Zoledronate reverses mandibular bone loss in osteoprotegerin-deficient mice
Zhi-Feng Sheng,Kang Xu,Yu-Lin Ma,J.-H. Liu,Ru-Chun Dai,Yu-Hai Zhang,Yebin Jiang,Er-Yuan Liao +7 more
TL;DR: It is shown that zoledronate could reverse the significant bone loss in mice mandibles that was induced by OPG gene deficiency and was independent of the OPG pathway.
Journal ArticleDOI
Periodontal Conditions in Elderly Men With and Without Osteoporosis or Osteopenia
Irma Shum,Ping-Chung Leung,Anthony W.L. Kwok,Esmonde F. Corbet,Eric S. Orwoll,Kathy R. Phipps,Lijian Jin +6 more
TL;DR: In this article, a case-control study was conducted to investigate the periodontal conditions in elderly men with and without osteoporosis or osteopenia and to determine their possible association with periodsontal destruction.
Journal ArticleDOI
Effect of ovarian activity on orthodontic tooth movement and gingival crevicular fluid levels of interleukin-1β and prostaglandin E2 in cats
TL;DR: It is indicated that ovarian activity can affect orthodontic tooth movement and GCF levels of IL-1β and PGE(2) in cats.
Journal ArticleDOI
Association between vitamin D receptor gene polymorphisms and chronic periodontitis among Libyans
Mouna M. El Jilani,Abdenaser A. Mohamed,Hamza Ben Zeglam,Inas M Alhudiri,Ahmad M. Ramadan,Saleh Suleiman Saleh,Mohamed Elkabir,Ibrahim Ben Amer,Nureddin Ashammakhi,Nabil Enattah +9 more
TL;DR: VDR ApaI SNP C/T rs#731236 may be related to the risk of CP in the Libyan population and this study examines 196 unrelated Libyans between the ages of 25 and 65 years.
References
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Journal ArticleDOI
A Long-Term Survey of Tooth Loss in 600 Treated Periodontal Patients
TL;DR: Patients in a private periodontal practice were reexamined an average of 22 years after their active treatment and the patterns of tooth loss were observed and tooth retention seemed more closely related to the case type than the surgery performed.
Journal ArticleDOI
Tooth Loss in 100 Treated Patients With Periodontal Disease: A Long-Term Study
TL;DR: periodontal disease appears to be bilaterally symmetrical and tooth loss response emulated this pattern with greatest loss of maxillary second molars and least loss of mandibular cuspids.
Journal ArticleDOI
Race and sex differences in hip fracture incidence.
TL;DR: Analysis based on an independent data source of non-federal hospital discharges in Washington, DC confirmed that White women were at twice the risk for hip fracture compared with Black women and at 2.7 times the risk compared to White men.
Journal ArticleDOI
The Bone Density of Female Twins Discordant for Tobacco Use
John L. Hopper,Ego Seeman +1 more
TL;DR: Whether a deficit in bone density is associated with tobacco use and, if so, to identify the responsible mechanisms is ascertained.
Journal ArticleDOI
Ovarian steroid treatment blocks a postmenopausal increase in blood monocyte interleukin 1 release.
Roberto Pacifici,Leonard Rifas,Ruth McCracken,Iris Vered,Cynthia T. McMurtry,Louis V. Avioli,William A. Peck +6 more
TL;DR: The hypothesis is that alterations in IL-1 production may underlie the postmenopausal acceleration in bone loss and its inhibition by ovarian steroids and is based on data from prospective and prospective studies.