Low- and moderate-dose non-cancer effects of ionizing radiation in directly exposed individuals, especially circulatory and ocular diseases: a review of the epidemiology.
TLDR
There are well-known correlations between high and moderate doses (>0.5 Gy) of ionizing radiation exposure and circulatory system damage, also between radiation and posterior subcapsular cataract.Abstract:
There are well-known correlations between high and moderate doses (>0.5 Gy) of ionizing radiation exposure and circulatory system damage, also between radiation and posterior subcapsular cataract. ...read more
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Areas of research to support the system of radiological protection.
Dominique Laurier,Werner Rühm,François Paquet,Kimberly E. Applegate,Donald Cool,Christopher Clement +5 more
TL;DR: The ICRP's updated vision on "Areas of research to support the System of Radiological Protection" as discussed by the authors was previously published in 2017, which aims to complement the research priorities promoted by other relevant international organisations, with the specificity of placing them in the perspective of the evolution of the system of radiological protection.
Journal ArticleDOI
Review of the risk of cancer following low and moderate doses of sparsely ionising radiation received in early life in groups with individually estimated doses
TL;DR: In this paper , the authors reviewed and summarised evidence from 60 studies of cancer or benign neoplasms following low- or moderate-level exposure in utero or in childhood from medical and environmental sources.
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Mortality and cancer incidence 1952–2017 in United Kingdom participants in the United Kingdom’s atmospheric nuclear weapon tests and experimental programmes
Michael Gillies,Richard Haylock +1 more
TL;DR: UK nuclear weapon tests participants have lower mortality rates compared to the national population although rates are slightly (2%) higher than in the study control group, and there was some evidence that participants had higher mortality rates from cerebrovascular diseases than those in the control group.
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Mortality from various diseases of the circulatory system in the Russian Mayak nuclear worker cohort: 1948–2018
TL;DR: The linear model that took into account non-radiation factors and alpha radiation dose did not demonstrate significant associations of mortality from DCS, ischaemic heart disease (IHD) and cerebrovascular disease with gamma-ray exposure dose in the entire cohort, the resident sub cohort or the migrant subcohort (either in men or women).
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Cardiac inflammation and fibrosis following chemo/radiation therapy: mechanisms and therapeutic agents.
TL;DR: In this article, the cellular and molecular mechanisms of cardiac inflammation and fibrosis following chemo/radiation therapy, and then review some adjuvants to reduce the risk of inflammation in the heart.
References
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Atherosclerosis — An Inflammatory Disease
TL;DR: Atherosclerosis is an inflammatory disease as discussed by the authors, and it is a major cause of death in the United States, Europe, and much of Asia, despite changes in lifestyle and use of new pharmacologic approaches to lower plasma cholesterol concentrations.
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Prediction of Coronary Heart Disease Using Risk Factor Categories
Peter W.F. Wilson,Ralph B. D'Agostino,Daniel Levy,Albert M. Belanger,Halit Silbershatz,William B. Kannel +5 more
TL;DR: A simple coronary disease prediction algorithm was developed using categorical variables, which allows physicians to predict multivariate CHD risk in patients without overt CHD.
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Inflammation in atherosclerosis
TL;DR: The new appreciation of the role of inflammation in atherosclerosis provides a mechanistic framework for understanding the clinical benefits of lipid-lowering therapies and unravelling the details of inflammatory pathways may eventually furnish new therapeutic targets.
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Risk of Ischemic Heart Disease in Women After Radiotherapy for Breast Cancer
Sarah C. Darby,Marianne Ewertz,Paul McGale,Anna M. Bennet,Ulla Blom-Goldman,Dorthe Scavenius Brønnum,C Correa,David J. Cutter,Giovanna Gagliardi,Bruna Gigante,Maj-Britt Jensen,Andrew Nisbet,Richard Peto,Kazem Rahimi,Carolyn W. Taylor,Per Hall +15 more
TL;DR: Exposure of the heart to ionizing radiation during radiotherapy for breast cancer increases the subsequent rate of ischemic heart disease, and the increase is proportional to the mean dose to the heart, begins within a few years after exposure, and continues for at least 20 years.
Journal ArticleDOI
Causes and prevalence of visual impairment among adults in the United States.
Nathan Congdon,O'Colmain Bj,Caroline C W Klaver,Ronald Klein,Beatriz Munoz,David S. Friedman,John H. Kempen,Hugh R. Taylor,Paul Mitchell +8 more
TL;DR: The prevalence of visual disabilities will increase markedly during the next 20 years, owing largely to the aging of the US population.