Open AccessJournal Article
Lycopersicon esculentum (Tomato) Prevents Adverse Effects of Lead on Blood Constituents.
Reads0
Chats0
TLDR
The oral administration of TP prevents the adverse effects of lead on blood constituents, and lead caused a significant increase in the percentage of neutrophils and the plasma malondialdehyde concentration, while TP, however, significantly prevented the adverse effect of LA.Abstract:
BACKGROUND Lead is known for its adverse effects on various organs and systems. In this study, the ability of lead to adversely affect blood parameters was investigated, and Lycopersicon esculentum, or commonly known as tomato (a source of antioxidants), was administered orally in the form of tomato paste (TP) to reduce the adverse effects of lead. METHODS The study involved 56 Wistar rats divided equally into 4 groups of 14 rats each: Control, LA(G), TP(G), and LA+TP(G). Control and TP(G) rats were given distilled water ad libitum, while LA(G) and LA+TP(G) rats were given 1% lead (II) acetate (LA) per day. TP(G) and LA+TP(G) rats were additionally treated with 1.5 ml of TP per day. All treatments lasted for 10 weeks, after which the rats were weighed and sacrificed, and haematological and biochemical parameters were measured. The independent samples t test was used to analyse the results. RESULTS LEAD CAUSED SIGNIFICANT REDUCTIONS IN THE FOLLOWING PARAMETERS: weight; packed cell volume; red blood cell and white blood cell counts; the percentages of lymphocytes and monocytes; total serum protein, albumin, and globulin levels; and plasma superoxide dismutase and catalase activities. In contrast, lead caused a significant increase in the percentage of neutrophils and the plasma malondialdehyde concentration. TP, however, significantly prevented the adverse effects of LA. CONCLUSION The oral administration of TP prevents the adverse effects of lead on blood constituents.read more
Citations
More filters
Journal ArticleDOI
Developing stress tolerant plants through in vitro selection—An overview of the recent progress
Manoj K. Rai,Rajwant K. Kalia,Rajwant K. Kalia,Rohtas Singh,Manu P. Gangola,Manu P. Gangola,A. K. Dhawan +6 more
TL;DR: The mechanisms of ROS (reaction oxygen species) generation and removal in plants under biotic and abiotic stress conditions have been reviewed and may be genetically stable and useful in crop improvement.
Journal ArticleDOI
Haemotoxic Effect of Lead: A Review
TL;DR: Chronic exposure to lead can result in a drastic changes in the cholesterol and phospholipid content, hexose, hexosamine and sialic acid levels and membrane acetyl cholinesterase, NADH dehydrogenase and Na+–K+ ATPase levels, which could reduce the severity of lead toxicity.
Journal ArticleDOI
The Preventive Approach of Biocompounactives (2): A Review in Recent Advances in Common Fruits
TL;DR: This second part of the review focuses on studies that have been conducted on biocompounactives of common fruits, and opportunities that present bioactivity of these phytochemicals to prevent many chronic diseases.
Journal ArticleDOI
Protective Role of Lycopene against Cadmium Induced Haematological Changes in Swiss Albino Mice
TL;DR: It is concluded that lycopene showed affordable protection against cadmium induced toxicity on blood profile and reversed almost all the abnormalities in the blood parameters showing significant protection against Cadmiuminduced toxicity in mice.
Journal Article
Carotenoid accumulation pattern and nutritional indices of Cherry-Nasmata and Var-10 tomato varieties.
TL;DR: In this paper, the accumulation pattern of lycopene and beta-carotene as well as the variation of the biochemical and physiological characteristics in Cherry-Nasmata and Var-10 tomato cultivars were studied.
References
More filters
Journal ArticleDOI
Colorimetric assay of catalase.
TL;DR: A simple colorimetric assay for catalase activity has been described using K2Cr2O7/acetic acid reagent to determine values of different enzyme sources and compared with the values obtained by titrimetric methods.
Journal ArticleDOI
Total Antioxidant Capacity of Fruits
TL;DR: In this article, the total antioxidant activity of 12 fruits and 5 commercial fruit juices was measured using automated oxygen radical absorbance capacity (ORAC) assay, and strawberry had the highest ORAC activity (micromoles of Trolox equivalents per gram).
Journal ArticleDOI
Lycopene in tomatoes: chemical and physical properties affected by food processing
John Shi,M Le Maguer +1 more
TL;DR: Determination of the degree of lycopene isomerization during processing would provide a measure of the potential health benefits of tomato-based foods, and further research on the bioavalability, pharmacology, biochemistry, and physiology must be done to reveal the mechanism of lyCopene in human diet.
Journal ArticleDOI
Lycopene is more bioavailable from tomato paste than from fresh tomatoes.
TL;DR: In humans, the bioavailability of lycopene is greater from tomato paste than from fresh tomatoes, and only the AUC response for the cis-isomers was significantly higher after ingestion of tomato paste.
Journal ArticleDOI
Effects of calmodulin antagonists on radiation-induced lipid peroxidation in microsomes.
R Varshney,R K Kale +1 more
TL;DR: Rat liver microsomes were irradiated with gamma-rays at a dose rate of 1.31 Gys-1.31 and calmodulin antagonists considerably inhibited radiation-induced lipid peroxidation in the presence of ferric (Fe3+) ions, which decreased the cytochrome P-450 content of microsome.