Journal ArticleDOI
Malignant transformation of oral lichen planus and oral lichenoid lesions: A meta-analysis of 20095 patient data.
Sana Maher Hasan Aghbari,Abdelrahman Ibrahim Abushouk,Attia O. Attia,Ahmed Elmaraezy,Amr Menshawy,Mohamed Shehata Ahmed,Basma Elsaadany,Eman Ahmed +7 more
TLDR
A higher incidence of malignant transformation was found among smokers, alcoholics, and HCV-infected patients; however, these associations should be further investigated.About:
This article is published in Oral Oncology.The article was published on 2017-05-01. It has received 190 citations till now. The article focuses on the topics: Oral lichen planus.read more
Citations
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Reply to "Is Vulvovaginal Lichen Planus Associated With Squamous Cell Carcinoma?"
TL;DR: The authors found no instance of lichen planus (LP) associated with SCC, whereas lichen sclerosus (LS), which resulted frequently misdiagnosed, was invariably associated with all SCC cases, and concluded that there are several reasons to doubt the association between genital LP and SCC.
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Follow‐up study of veterans with white and red oral mucosal lesions at Veterans Affairs Dental Clinics
Robert S. Feldman,Scott R. Diehl,Trina Jones-Richardson,Rebeka G Silva,Chih Ko Yeh,Kevin J Malley,Sam E. Farish,Mary B. Duffy,Robert M. Craig,Deborah M. Winn +9 more
TL;DR: This paper examined clinical and histopathological characteristics of white and red oral mucosal lesions and patient lifestyle behaviors to understand how the lesions changed over 19-23 years, including among patients who developed oral and pharyngeal cancer.
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Necrobiotic xanthogranuloma developing in a patient with diffuse normolipemic plane xanthoma: association of two monoclonal gammopathy‐related disorders
TL;DR: The profound clinical response seen in this patient further implicates the IL-23/ IL-17 pathway in the pathogenesis of OLP and suggests that tildrakizumab may be a potential treatment option for OLP, although larger studies are needed to support these findings.
Treatment with Calcineurin Inhibitors of Oral Lichen Planus. An Attempt to Clarify the Issue.
TL;DR: The author believe that patients with erosive lichen planus should be immediately biopsied and topical calcineurin inhibitors prescribed to ameliorate the severe impairment of the quality of life.
References
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Bias in meta-analysis detected by a simple, graphical test
TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
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Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses
TL;DR: The quality assessment of non-randomized studies is an important component of a thorough meta-analysis of non randomized studies and can dramatically influence the interpretation of meta-analyses, and can even reverse conclusions regarding the effectiveness of an intervention.
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Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG.
TL;DR: DCMP and dAMP are incorporated selectively opposite 8-oxodG with transient inhibition of chain extension occurring 3' to the modified base, and the potentially mutagenic insertion of dAMP is targeted exclusively to the site of the lesion.