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Journal ArticleDOI

Mammogram segmentation by contour searching and massive lesion classification with neural network

TLDR
An algorithm for detecting masses in mammographic images acquired in several hospitals belonging to the MAGIC-5 collaboration by means of a ROI Hunter algorithm, without loss of meaningful information is presented.
Abstract
The mammography is the most effective procedure for an early diagnosis of the breast cancer. In this paper, an algorithm for detecting masses in mammographic images will be presented. The database consists of 3762 digital images acquired in several hospitals belonging to the MAGIC-5 collaboration (Medical Applications on a Grid Infrastructure Connection). A reduction of the whole image's area under investigation is achieved through a segmentation process, by means of a ROI Hunter algorithm, without loss of meaningful information. In the following classification step, feature extraction plays a fundamental role: some features give geometrical information, other ones provide shape parameters. Once the features are computed for each ROI, they are used as inputs to a supervised neural network with momentum. The output neuron provides the probability that the ROI is pathological or not. Results are provided in terms of ROC and FROC curves: the area under the ROC curve was found to be AZ=0.862plusmn0.007, and we get a 2.8 FP/Image at a sensitivity of 82%. This software is included in the CAD station actually working in the hospitals belonging to the MAGIC-5 Collaboration

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Citations
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Journal ArticleDOI

A review of automatic mass detection and segmentation in mammographic images.

TL;DR: The aim of this paper is to review existing approaches to the automatic detection and segmentation of masses in mammographic images, highlighting the key-points and main differences between the used strategies.
Journal ArticleDOI

A hybrid intelligent system for medical data classification

TL;DR: A hybrid intelligent system that consists of the Fuzzy Min-Max neural network, the Classification and Regression Tree, and the Random Forest model is proposed, and its efficacy as a decision support tool for medical data classification is examined.
Journal ArticleDOI

Automatic detection of lung nodules in CT datasets based on stable 3D mass-spring models

TL;DR: An advanced computerized method for the automatic detection of internal and juxtapleural nodules on low-dose and thin-slice lung CT scan and the use of the 3D AC model and the feature analysis based FPs reduction process constitutes an accurate approach to the segmentation and the classification of lung nodules.
Journal ArticleDOI

Detection of Suspicious Lesions by Adaptive Thresholding Based on Multiresolution Analysis in Mammograms

TL;DR: A novel algorithm to detect suspicious lesions in mammograms that utilizes the combination of adaptive global thresholding segmentation and adaptive local thresholded segmentation on a multiresolution representation of the original mammogram is developed.
Journal ArticleDOI

A CAD system for nodule detection in low-dose lung CTs based on region growing and a new active contour model

TL;DR: A computer-aided detection system for the selection of lung nodules in computer tomography (CT) images is presented, based on region growing (RG) algorithms and a new active contour model (ACM), able to draw the correct contour of the lung parenchyma and to include the pleural nodules.
References
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Book

Neural Networks: A Comprehensive Foundation

Simon Haykin
TL;DR: Thorough, well-organized, and completely up to date, this book examines all the important aspects of this emerging technology, including the learning process, back-propagation learning, radial-basis function networks, self-organizing systems, modular networks, temporal processing and neurodynamics, and VLSI implementation of neural networks.
Journal ArticleDOI

The meaning and use of the area under a receiver operating characteristic (ROC) curve.

James A. Hanley, +1 more
- 01 Apr 1982 - 
TL;DR: A representation and interpretation of the area under a receiver operating characteristic (ROC) curve obtained by the "rating" method, or by mathematical predictions based on patient characteristics, is presented and it is shown that in such a setting the area represents the probability that a randomly chosen diseased subject is (correctly) rated or ranked with greater suspicion than a random chosen non-diseased subject.
Journal ArticleDOI

A method of comparing the areas under receiver operating characteristic curves derived from the same cases.

James A. Hanley, +1 more
- 01 Sep 1983 - 
TL;DR: This paper refines the statistical comparison of the areas under two ROC curves derived from the same set of patients by taking into account the correlation between the areas that is induced by the paired nature of the data.
Journal ArticleDOI

Analysis of cancers missed at screening mammography.

R E Bird, +2 more
- 01 Sep 1992 - 
TL;DR: Analysis of 320 cancers found in a screened population between August 1985 and May 1990 revealed 77 cancers that were "missed" at screening mammography, which occurred in women with denser breasts, were less likely to demonstrate malignant microcalcifications, and were more likely to demonstrating a developing opacity as an indication of cancer.
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