Manufactured nanomaterials (fullerenes, C60) induce oxidative stress in the brain of juvenile largemouth bass.
Reads0
Chats0
TLDR
This is the first study showing that uncoated fullerenes can cause oxidative damage and depletion of GSH in vivo in an aquatic species, and further research needs to be done to evaluate the potential toxicity of manufactured nanomaterials, especially with respect to translocation into the brain.Abstract:
Although nanotechnology has vast potential in uses such as fuel cells, microreactors, drug delivery devices, and personal care products, it is prudent to determine possible toxicity of nanotechnolo...read more
Citations
More filters
Journal ArticleDOI
Toxic Potential of Materials at the Nanolevel
TL;DR: The establishment of principles and test procedures to ensure safe manufacture and use of nanomaterials in the marketplace is urgently required and achievable.
Journal ArticleDOI
Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles
TL;DR: Results of older bio-kinetic studies with NSPs and newer epidemiologic and toxicologic studies with airborne ultrafine particles can be viewed as the basis for the expanding field of nanotoxicology, which can be defined as safety evaluation of engineered nanostructures and nanodevices.
Journal ArticleDOI
Microplastics in the marine environment
TL;DR: The mechanisms of generation and potential impacts of microplastics in the ocean environment are discussed, and the increasing levels of plastic pollution of the oceans are understood, it is important to better understand the impact of microPlastic in the Ocean food web.
Journal ArticleDOI
Drug delivery and nanoparticles:applications and hazards
Wim H. de Jong,Paul J A Borm +1 more
TL;DR: An overview on some of the currently used systems for drug delivery, varying from biological substances like albumin, gelatine and phospholipids for liposomes, and more substances of a chemical nature like various polymers and solid metal containing nanoparticles is provided.
Posted Content
Nanomaterials and nanoparticles: Sources and toxicity
TL;DR: A review of the toxicity of nanoparticles is presented in this paper, with the goal of informing public health concerns related to nanoscience while raising awareness of nanomaterials toxicity among scientists and manufacturers handling them.
References
More filters
Journal ArticleDOI
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
TL;DR: This assay is very reproducible and rapid with the dye binding process virtually complete in approximately 2 min with good color stability for 1 hr with little or no interference from cations such as sodium or potassium nor from carbohydrates such as sucrose.
Journal ArticleDOI
Probing the Cytotoxicity Of Semiconductor Quantum Dots.
TL;DR: This work found that CdSe-core QDs were indeed acutely toxic under certain conditions and modulated by processing parameters during synthesis, exposure to ultraviolet light, and surface coatings, and suggests that cytotoxicity correlates with the liberation of free Cd2+ ions due to deterioration of the Cd Se lattice.
Book ChapterDOI
Determination of glutathione and glutathione disulfide in biological samples.
TL;DR: 5,5'-dithiobis(2-nitrobenzoic acid) (DTNB)-GSSG reductase recycling assay for total glutathione is a specific, sensitive, rapid, and reliable procedure, however, because the method depends on an accurate standard curve, appropriate standards containing the protein precipitating agent are essential.
Journal ArticleDOI
Translocation of Inhaled Ultrafine Particles to the Brain
Günter Oberdörster,Zachary D. Sharp,Viorel Atudorei,Alison Elder,Robert Gelein,Wolfgang G. Kreyling,Christopher Cox +6 more
TL;DR: The study concludes that the central nervous system (CNS) can be targeted by airborne solid ultrafine particles and that the most likely mechanism is from deposits on the olfactory mucosa of the nasopharyngeal region of the respiratory tract and subsequent translocation via the Olfactory nerve.
Journal ArticleDOI
The potential environmental impact of engineered nanomaterials
TL;DR: With the increased presence of nanomaterials in commercial products, a growing public debate is emerging on whether the environmental and social costs of nanotechnology outweigh its many benefits.