Journal ArticleDOI
Medicinal mushrooms: Clinical perspective and challenges
TLDR
In this article , a review of clinical studies on medicinal mushrooms or preparations derived thereof is presented, and the authors conclude that despite the promising published clinical data, especially on immune modulation, more work is required to clarify the therapeutic value of mushrooms.About:
This article is published in Drug Discovery Today.The article was published on 2022-02-01. It has received 15 citations till now. The article focuses on the topics: Clinical trial & Medicine.read more
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Journal ArticleDOI
Edible Mushrooms for Sustainable and Healthy Human Food: Nutritional and Medicinal Attributes
Hassan El-Ramady,Neama Abdalla,Khandsuren Badgar,Xhensila Llanaj,Gréta Törős,Péter Hajdu,Yahya Z. Eid,József Prokisch +7 more
TL;DR: In this article , the authors focus on sustainable approaches for handling edible mushrooms and their secondary metabolites, including bio-fortification, and compare between edible and poisonous mushrooms, as well as the common species of edible mushrooms, and their different bioactive ingredients.
Journal ArticleDOI
Anticancer Activities of Mushrooms: A Neglected Source for Drug Discovery
TL;DR: This review aims to provide a critical discussion on clinical trial evidence for mushrooms to treat patients with diverse types of cancer, and highlights the identified bioactive compounds and corresponding mechanisms of action among the explored mushrooms.
Journal ArticleDOI
Vegan nutrition: a preliminary guide for health professionals.
TL;DR: The aim of this article is to provide vegan nutrition guidelines, based on current evidence, which can easily be communicated to vegan patients/clients, with the goal of ensuring adequate nutrient status in vegans.
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Filamentous fungi for sustainable vegan food production systems within a circular economy: Present status and future prospects.
Mukesh Kumar Awasthi,Vinay Kumar,Coralie Hellwig,Rachma Wikandari,Sharareh Harirchi,Taner Sar,Steven Wainaina,Raveendran Sindhu,Parameswaran Binod,Zengqiang Zhang,Mohammad J. Taherzadeh +10 more
TL;DR: In this paper , the potential of filamentous fungi as a source of food and food supplements is discussed and the commercialization potential as well as social, legal and safety issues of fungi-based food products are discussed.
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Recent advances in the bioactive polysaccharides and other key components from Phellinus spp. and their pharmacological effects: A review.
TL;DR: A review of physicochemical characteristics, pharmacological activities, and possible mechanisms of bioactive components from Phellinus spp. according to published studies from 2017 to 2022 is presented in this article .
References
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Journal ArticleDOI
Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides.
TL;DR: The present review analyzes the pecularities of polysaccharides derived from fruiting bodies and cultured mycelium in selected examples of medicinal mushrooms and concludes that high molecular weight glucans appear to be more effective than those of low molecular weight.
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Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study
Robin L. Carhart-Harris,Mark Bolstridge,James Rucker,Camilla M. Day,David Erritzoe,Mendel Kaelen,Michael A P Bloomfield,James Rickard,Ben Forbes,Amanda Feilding,David Taylor,Steve Pilling,Valerie Curran,David J. Nutt +13 more
TL;DR: Preliminary support for the safety and efficacy of psilocybin for treatment-resistant depression is provided and motivates further trials, with more rigorous designs, to better examine the therapeutic potential of this approach.
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The effects of β-glucan on human immune and cancer cells
TL;DR: No good quality clinical trial data is available on assessing the effectiveness of purified β-glucans among cancer patients, so future effort should direct at performing well-designed clinical trials to verify the actual clinical efficacy of β- Glucans or β- glucans containing compounds.
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Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double‐blind placebo‐controlled clinical trial
TL;DR: The results obtained in this study suggest that Yamabushitake is effective in improving mild cognitive impaired men and women diagnosed with mild cognitive impairment.
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A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effects
Gary Deng,Hong Lin,Andrew D. Seidman,Monica Fornier,Gabriella D'Andrea,Kathleen M. Wesa,Simon Yeung,Susanna Cunningham-Rundles,Andrew J. Vickers,Barrie R. Cassileth +9 more
TL;DR: Oral administration of a polysaccharide extract from Maitake mushroom is associated with both immunologically stimulatory and inhibitory measurable effects in peripheral blood, and cancer patients should be made aware of the fact that botanical agents produce more complex effects than assumed, and may depress as well as enhance immune function.