Microfluidics without pumps: reinventing the T-sensor and H-filter in paper networks
TLDR
This work revisits well-known microfluidic devices for hydrodynamic focusing, sized-based extraction of molecules from complex mixtures, micromixing, and dilution, and demonstrates that paper-based devices can replace their expensive conventional micro fluidic counterparts.Abstract:
Conventional microfluidic devices typically require highly precise pumps or pneumatic control systems, which add considerable cost and the requirement for power. These restrictions have limited the adoption of microfluidic technologies for point-of-care applications. Paper networks provide an extremely low-cost and pumpless alternative to conventional microfluidic devices by generating fluid transport through capillarity. We revisit well-known microfluidic devices for hydrodynamic focusing, sized-based extraction of molecules from complex mixtures, micromixing, and dilution, and demonstrate that paper-based devices can replace their expensive conventional microfluidic counterparts.read more
Citations
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Journal ArticleDOI
Paper-based microfluidic point-of-care diagnostic devices
TL;DR: This review includes challenges to scaling up, commercialisation and regulatory issues, and the factors which limit paper-based microfluidic devices to become real world products and future directions are also identified.
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Commercialization of microfluidic point-of-care diagnostic devices
TL;DR: Current work in commercializing microfluidic technologies is reviewed, with a focus on point-of-care diagnostics applications, and the need to strike a balance between achieving real-world impact with integrated devices versus design of novel single microfluidity components is discussed.
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Point of care diagnostics: Status and future
TL;DR: This chapter discusses the development of personalized medicine and home testing in the developing world, and some of the strategies used to achieve this goal have not yet been developed.
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Recent developments in paper-based microfluidic devices.
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Advances in microfluidic materials, functions, integration, and applications.
TL;DR: The successful demonstration of electrophoresis and electroosmotic pumping in a microfluidic device provided a nonmechanical method for both fluid control and separation, and integration of multiple processes can be highly enabling for many applications.
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