Three-dimensional microfluidic devices fabricated in layered paper and tape.
TLDR
A method for fabricating 3D microfluidic devices by stacking layers of patterned paper and double-sided adhesive tape to carry out a range of new analytical protocols simply and inexpensively without external pumps is described.Abstract:
This article describes a method for fabricating 3D microfluidic devices by stacking layers of patterned paper and double-sided adhesive tape. Paper-based 3D microfluidic devices have capabilities in microfluidics that are difficult to achieve using conventional open-channel microsystems made from glass or polymers. In particular, 3D paper-based devices wick fluids and distribute microliter volumes of samples from single inlet points into arrays of detection zones (with numbers up to thousands). This capability makes it possible to carry out a range of new analytical protocols simply and inexpensively (all on a piece of paper) without external pumps. We demonstrate a prototype 3D device that tests 4 different samples for up to 4 different analytes and displays the results of the assays in a side-by-side configuration for easy comparison. Three-dimensional paper-based microfluidic devices are especially appropriate for use in distributed healthcare in the developing world and in environmental monitoring and water analysis.read more
Citations
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Diagnostics for the Developing World: Microfluidic Paper-Based Analytical Devices
TL;DR: Microfluidic paper-based analytical devices are a new class of point-of-care diagnostic devices that are inexpensive, easy to use, and designed specifically for use in developing countries.
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The present and future role of microfluidics in biomedical research
TL;DR: The progress made by lab-on-a-chip microtechnologies in recent years is analyzed, and the clinical and research areas in which they have made the greatest impact are discussed.
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Paper-based microfluidic point-of-care diagnostic devices
TL;DR: This review includes challenges to scaling up, commercialisation and regulatory issues, and the factors which limit paper-based microfluidic devices to become real world products and future directions are also identified.
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Understanding wax printing: a simple micropatterning process for paper-based microfluidics.
TL;DR: A detailed study on wax printing, a simple and inexpensive method for fabricating microfluidic devices in paper using a commercially available printer and hot plate, which creates complete hydrophobic barriers in paper that define hydrophilic channels, fluid reservoirs, and reaction zones.
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Highly conductive paper for energy-storage devices
TL;DR: It is suggested that this conductive paper can be a highly scalable and low-cost solution for high-performance energy storage devices and as an excellent lightweight current collector in lithium-ion batteries to replace the existing metallic counterparts.
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