Journal ArticleDOI
Microsatellite analysis of Toxoplasma gondii shows considerable polymorphism structured into two main clonal groups
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TLDR
Evolutionary genetic analyses of diversity show that the T. gondii population structure consists of only two clonal lineages that can be equated to discrete typing units, but there is some evidence of occasional genetic exchange that could explain why one of these discrete typed units is less clearly individualised than the other.About:
This article is published in International Journal for Parasitology.The article was published on 2002-01-01. It has received 277 citations till now. The article focuses on the topics: Restriction fragment length polymorphism & Microsatellite.read more
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Journal ArticleDOI
Epidemiology of and Diagnostic Strategies for Toxoplasmosis
TL;DR: This review focuses on epidemiological and diagnostic aspects, putting them in perspective with current knowledge of parasite genotypes, and provides critical information on diagnostic methods according to the patient's background.
Journal ArticleDOI
Moving towards an integrated approach to molecular detection and identification of Toxoplasma gondii.
TL;DR: This review discusses some widely used molecular methods and proposes an integrated approach for the detection and identification of T. gondii, in order to generate maximum information for epidemiological, population and phylogenetic studies of this key pathogen.
Journal ArticleDOI
Genotype of 86 Toxoplasma gondii Isolates Associated with Human Congenital Toxoplasmosis, and Correlation with Clinical Findings
Daniel Ajzenberg,Nadine Cogné,Luc Paris,Marie-Hélène Bessières,Philippe Thulliez,Denis Filisetti,Hervé Pelloux,Pierre Marty,Marie-Laure Dardé +8 more
TL;DR: To study the influence of Toxoplasma gondii genotypes on the severity of human congenital toxoplasmosis (asymptomatic, benign, or severe infection or newborn or fetal death), 8 microsatellite markers were used and type II isolates were largely predominant.
Journal ArticleDOI
Globalization and the population structure of Toxoplasma gondii
TL;DR: The evidence suggests that South American and Eurasian populations have evolved separately until recently, when ships populated by rats, mice, and cats provided T. gondii with unprecedented migration opportunities, probably during the transatlantic slave trade.
Journal ArticleDOI
Genotyping of Toxoplasma gondii by multilocus PCR-RFLP markers: A high resolution and simple method for identification of parasites
TL;DR: Nine PCR-restriction fragment length polymorphism markers with each of them capable of distinguishing the three archetypal T. gondii alleles in one restriction-enzyme reaction by agarose gel electrophoresis are developed and showed that they could readily distinguish the archetyPal from atypical types and reveal the genetic diversity of the parasites.
References
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The neighbor-joining method: a new method for reconstructing phylogenetic trees.
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TL;DR: The neighbor-joining method and Sattath and Tversky's method are shown to be generally better than the other methods for reconstructing phylogenetic trees from evolutionary distance data.
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The Detection of Disease Clustering and a Generalized Regression Approach
TL;DR: The technic to be given below for imparting statistical validity to the procedures already in vogue can be viewed as a generalized form of regression with possible useful application to problems arising in quite different contexts.
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Molecular Markers, Natural History, and Evolution
TL;DR: A history of Molecular Phylogenetics and applications of individuality and Parentage, issues of Heterozygosity, and special Approaches to Phylageny Estimation are reviewed.
Journal ArticleDOI
Molecular Markers, Natural History and Evolution.
A. C. M. Gillies,John C. Avise +1 more
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