Journal ArticleDOI
Mixed connective tissue disease-an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA)
TLDR
The detection of antibody to ENA with a well defined specificity allows recognition of an apparently distinct mixed connective tissue disease syndrome which is characterized by an excellent response to corticosteroid therapy and a favorable prognosis.About:
This article is published in The American Journal of Medicine.The article was published on 1972-02-01. It has received 1632 citations till now. The article focuses on the topics: Mixed connective tissue disease & Extractable nuclear antigens.read more
Citations
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Journal ArticleDOI
Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group
Claudio Vitali,Stefano Bombardieri,Roland Jonsson,Haralampos M. Moutsopoulos,E L Alexander,Steven E. Carsons,Troy E. Daniels,P C Fox,Robert I. Fox,Stuart S. Kassan,S R Pillemer,Norman Talal,M H Weisman +12 more
TL;DR: These classification criteria for Sjögren's syndrome have been re-examined by consensus group members, who have introduced some modifications, more clearly defined the rules for classifying patients with primary or secondary SS, and provided more precise exclusion criteria.
Journal ArticleDOI
Preliminary criteria for the classification of systemic sclerosis (scleroderma)
TL;DR: A multicenter, ongoing study of early-diagnosed cases of systemic sclerosis and comparison patients with systemic lupus erythematosus, polymyositis/dermatomyositis, and Raynaud's phenomenon was conducted in order to develop classification criteria for systemic sclerosis.
Journal ArticleDOI
Preliminary criteria for the classification of Sjögren's syndrome. Results of a prospective concerted action supported by the European Community.
Claudio Vitali,Stefano Bombardieri,Haralampos M. Moutsopoulos,Genesio Balestrieri,Walter Bencivelli,Robert M. Bernstein,Kirsten B. Bjerrum,Susanna Braga,J Coll,Salvatore De Vita,Alexandros A. Drosos,Michael Ehrenfeld,Pierre Y. Hatron,Elaine M Hay,David A. Isenberg,Anne Janin,Joachim R. Kalden,Louis Kater,Yrjö T. Konttinen,Peter J. Maddison,Ravinder N. Maini,Rolf Manthorpe,Olivier Meyer,Pierantonio Ostuni,Y.L. Pennec,Jan Ulrik Prause,Andrea Richards,Bernard Sauvezie,Morten Schiødt,Maria Sciuto,Crispian Scully,Yehuda Shoenfeld,Fotini N. Skopouli,Josef S. Smolen,M L Snaith,Moshe Tishler,Silvano Todesco,Guido Valesini,Patrick J Venables,Marie J. Wattiaux,Pierre Youinou +40 more
TL;DR: Using the findings of this prospective multicenter European study, general agreement can be reached on the diagnostic procedures to be used for patients with SS.
Book ChapterDOI
Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology
TL;DR: One of the purposes of this chapter is to show that the new molecular biology of cellular antigens and auto-antibodies could now be providing insights into comprehending some features of autoimmunity.
Journal ArticleDOI
Immunoblotting and dot immunobinding--current status and outlook.
Harry Towbin,J. Gordon +1 more
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid
TL;DR: The present study arose from the observation that a more intense colour was sometimes produced if, instead of being heated at 1000 for 10 min., the reaction mixture was allowed to stand overnight at room temperature.
Journal ArticleDOI
Immunochemical quantitation of antigens by single radial immunodiffusion
TL;DR: By standardizing the technical conditions of the experiment it is possible to use this principle for the immunochemical determination of antigens, and the lower limit of the method was found to correspond to 0·0025 μg of antigen, and to an antigen concentrations of 1·25 μg per ml.
Journal ArticleDOI
Determination of nucleic acids in animal tissues
TL;DR: A modification of the Barrenscheen and Peham method for ribose determination with orcinol was worked out in order to determine pentose nucleic acid (PNA) in the same organ extracts, which permitted the evaluation of DNA in amounts as small as 2.5 y per ml.
Journal ArticleDOI
Pathologic observations in systemic sclerosis (scleroderma). A study of fifty-eight autopsy cases and fifty-eight matched controls
TL;DR: The organs found to be frequently and significantly involved by systemic sclerosis were the skin, gastrointestinal tract, lungs, kidneys, skeletal muscle and pericardium, and atrophy was usually a more prominent finding than was fibrosis in organs containing smooth muscle.
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