Journal ArticleDOI
Molecular mechanisms of bioactive polysaccharides from Ganoderma lucidum (Lingzhi), a review.
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TLDR
The aim of this review is to update and summarize the mechanisms of the various bioactive polysaccharides extracted from G. lucidum and should be valuable in the research and development of GLPs-derived therapeutics.About:
This article is published in International Journal of Biological Macromolecules.The article was published on 2020-05-01. It has received 103 citations till now.read more
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Natural products as home-based prophylactic and symptom management agents in the setting of COVID-19.
TL;DR: Natural products like ginger, turmeric, garlic, onion, cinnamon, lemon, neem, basil, and black pepper have been scientifically proven to have therapeutic benefits against acute respiratory tract infections including pulmonary fibrosis, diffuse alveolar damage, pneumonia, and acute respiratory distress syndrome, all of which are symptoms associated with COVID‐19 infection.
Journal ArticleDOI
Advances in dietary polysaccharides as anticancer agents: Structure-activity relationship
Ningyang Li,Chaofan Wang,Milen I. Georgiev,Milen I. Georgiev,Vivek K. Bajpai,Rosa Tundis,Jesus Simal-Gandara,Lu Xiaoming,Jianbo Xiao,Xiaozhen Tang,Xuguang Qiao +10 more
TL;DR: It is important for human to resist tumors by elucidating the antitumor effects of polysaccharides from different resources and their correlation, discussing the application of anticancer poly Saccharides in combination with chemotherapy drugs and anticancer vaccine adjuvants.
Journal ArticleDOI
Polysaccharides from Auricularia auricula: Preparation, structural features and biological activities.
TL;DR: This review has summarized current knowledge about extraction and purification methods, structural features, biological activities and potential molecular mechanisms of A. auricula, and the proposed structure-activity relationships of AAPs.
Journal ArticleDOI
Advances in the extraction, purification, structural-property relationships and bioactive molecular mechanism of Flammulina velutipes polysaccharides: A review
Yongxia Wang,Hua Zhang +1 more
TL;DR: The current progress in the extraction, purification, structural characteristics and bioactivities of F. velutipes polysaccharides (FVPs) were reviewed and the structural-property relationships of FVPs were further discussed.
References
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Journal ArticleDOI
The effects of β-glucan on human immune and cancer cells
TL;DR: No good quality clinical trial data is available on assessing the effectiveness of purified β-glucans among cancer patients, so future effort should direct at performing well-designed clinical trials to verify the actual clinical efficacy of β- Glucans or β- glucans containing compounds.
Journal ArticleDOI
Mechanism by Which Orally Administered -1,3-Glucans Enhance the Tumoricidal Activity of Antitumor Monoclonal Antibodies in Murine Tumor Models 1
Feng Hong,Jun Yan,Jarek Baran,Daniel J. Allendorf,Richard Hansen,Gary R. Ostroff,Pei Xiang Xing,Nai-Kong V. Cheung,Gordon D. Ross +8 more
TL;DR: This investigation showed that orally administered yeast β-1,3;1,6-glucan functioned similarly to barley β- 1,1,4- glucan with antitumor mAb, and a requirement for iC3b on tumors and CR3 on granulocytes was confirmed by demonstrating therapeutic failures in mice deficient in C3 or CR3.
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Antitumor polysaccharides from mushrooms: a review on the structural characteristics, antitumor mechanisms and immunomodulating activities.
Xin Meng,Hebin Liang,Lixin Luo +2 more
TL;DR: This review covers existing research achievements on the mechanisms of isolated mushroom polysaccharides, particularly (1→3)-β-D-glucans, and describes the function in modulating the immune system and potential tumor-inhibitory effects of polySaccharides.
Journal ArticleDOI
Ganoderma lucidum polysaccharides: immunomodulation and potential anti-tumor activities.
TL;DR: This paper examines the potential role of G. lucidum polysaccharide (GLPS) in tumor therapy and the possible mechanisms involved and suggests that the anti-tumor activities of GLPS are mediated by its immunomodulatory, anti-angiogenic, and cytotoxic effects.