Journal ArticleDOI
Multicomponent reactions for the synthesis of pyrroles
TLDR
Multicomponent reactions are one of the most interesting concepts in modern synthetic chemistry and provide an attractive entry into pyrrole derivatives, which are very important heterocycles from many points of view.Abstract:
Multicomponent reactions are one of the most interesting concepts in modern synthetic chemistry and, as shown in this critical review, they provide an attractive entry into pyrrole derivatives, which are very important heterocycles from many points of view including medicinal and pharmaceutical chemistry and materials science (97 references).read more
Citations
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Visible-Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
TL;DR: This Review compares classical and photocatalytic procedures for selected classes of reactions and highlights their advantages and limitations.
Journal ArticleDOI
Transition Metal-Mediated Synthesis of Monocyclic Aromatic Heterocycles
TL;DR: The present review is a transition metal-catalyzed synthesis of aromatic monocyclic heterocycles, aiming at achieving greater levels of molecular complexity and better functional group compatibilities in a convergent and atom economical fashions from readily accessible starting materials and under mild reaction conditions.
Journal ArticleDOI
Bond Activation and Catalysis by Ruthenium Pincer Complexes
TL;DR: The heterolytic activation of dihydrogen by NH/H2 MLC was reported by Fryzuk and co-workers in 1987 with pincer Ir and Rh complexes, and complex 73 was found to be an active dehydrogenation catalyst for ammoniaborane and hydrogenation reactions as discussed below.
Journal ArticleDOI
Recent developments in asymmetric multicomponent reactions.
TL;DR: Significantly broadened scopes, new techniques, more environmentally benign methods and entirely novel MCRs reflect the increasingly inventive paths that synthetic chemist follow in this field of asymmetric multicomponent reactions.
Journal ArticleDOI
Recent advances in the synthesis of pyrroles by multicomponent reactions
TL;DR: This work describes the progress made in this area in the period between mid-2009 and the end of 2013 by describing the ready availability of suitably substituted and functionalized pyrrole derivatives.
References
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Journal ArticleDOI
BODIPY dyes and their derivatives: syntheses and spectroscopic properties.
Aurore Loudet,Kevin Burgess +1 more
Journal ArticleDOI
Recent developments in isocyanide based multicomponent reactions in applied chemistry
Journal ArticleDOI
Natural product synthesis using multicomponent reaction strategies.
B. Barry Touré,Dennis G. Hall +1 more
TL;DR: The preparation of urea by Wöhler constituted a landmark achievement in organic chemistry, and it laid the ground for the early days of target-oriented organic synthesis, a task deemed inconceivable by early practitioners.
Journal ArticleDOI
A Planning Strategy for Diversity‐Oriented Synthesis
TL;DR: Although the distinct goals of DOS do not permit the application of retrosynthetic concepts and thinking, these foundations are being built on, by using parallel logic, to develop a complementary procedure known as forward-Synthetic analysis, which facilitates synthetic planning, communication, and teaching in this evolving discipline.
Journal ArticleDOI
"Multi-component reactions : emerging chemistry in drug discovery" 'from xylocain to crixivan'.
TL;DR: This review details developments of new, highly atom-economic MCR derived chemical methods, which enable the fast and efficient production of chemical libraries comprised of a variety of biologically relevant templates, and focuses on applications of isocyanide based MCR (IMCR) reactions.