Journal ArticleDOI
Myelinated nerve fibers: computed effect of myelin thickness on conduction velocity
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This article is published in American Journal of Physiology.The article was published on 1970-11-01. It has received 195 citations till now. The article focuses on the topics: Myelinated nerve fiber & Neural Conduction.read more
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Journal ArticleDOI
Neuronal Activity Promotes Oligodendrogenesis and Adaptive Myelination in the Mammalian Brain
Erin M. Gibson,David Purger,Christopher Mount,Andrea K. Goldstein,Grant L. Lin,Lauren Wood,Ingrid Inema,Sarah E. Miller,Gregor Bieri,J. Bradley Zuchero,Ben A. Barres,Pamelyn Woo,Hannes Vogel,Michelle Monje +13 more
TL;DR: In vivo optogenetic techniques in awake, behaving mice are used to provide direct evidence that neuronal activity regulates changes in myelin-forming cells within an active circuit, suggesting that adaptive changes inMyelin-form cells represent a type of behaviorally relevant neural plasticity.
Journal ArticleDOI
White matter maturation reshapes structural connectivity in the late developing human brain
Patric Hagmann,Olaf Sporns,Neel Madan,Leila Cammoun,Rudolph Pienaar,Van J. Wedeen,Reto Meuli,Jean-Philippe Thiran,Patricia Ellen Grant +8 more
TL;DR: The strengthening of the correlation between structural and functional connectivity with age suggests that white matter connectivity in combination with other factors, such as differential modulation of axonal diameter and myelin thickness, play an increasingly important role in creating brain-wide coherence and synchrony.
Journal ArticleDOI
Determinants of conduction velocity in myelinated nerve fibers.
TL;DR: The conduction speed of any given fiber reflects a number of parameters and is not determined by any single structural characteristic.
Journal ArticleDOI
Contactin Orchestrates Assembly of the Septate-like Junctions at the Paranode in Myelinated Peripheral Nerve
Mary E.T. Boyle,Erik O. Berglund,Keith K. Murai,Keith K. Murai,Lynne Weber,Lynne Weber,Elior Peles,Barbara Ranscht,Barbara Ranscht +8 more
TL;DR: GPI-linked contactin enables the formation of the paranodal septate-like axo-glial junctions in myelinated peripheral nerve and is a crucial part in the machinery that controls junctional attachment at the paranode and ultimately the physiology of myelinate nerve.
Journal ArticleDOI
Characterization of cerebral white matter properties using quantitative magnetic resonance imaging stains.
Andrew L. Alexander,Samuel A. Hurley,Alexey Samsonov,Nagesh Adluru,Ameer Pasha Hosseinbor,Pouria Mossahebi,Do P.M. Tromp,Elizabeth Zakszewski,Aaron S. Field +8 more
TL;DR: Three quantitative MRI methods for characterizing white matter (WM) microstructural properties are reviewed, all of which measure complementary aspects of how water interacts with the tissue environment.
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