Journal ArticleDOI
Nanomagnetically modified ferric hydrogen sulfate (NiFe2O4@SiO2-FHS): a reusable green catalyst for the synthesis of highly functionalized piperidine derivatives
Mohammad Rahimizadeh,Seyed Mohammad Seyedi,Mohsen Abbasi,Hossein Eshghi,Amir Khojastehnezhad,Farid Moeinpour,Mehdi Bakavoli +6 more
TLDR
An efficient and one-pot multi-component procedure for the preparation of functionalized piperidine derivatives from reactions of aromatic aldehydes, substituted anilines and ethyl acetoacetate in the presence of ferric hydrogen sulfate-supported silica-coated magnetic nanoparticles (NiFe2O4@SiO2-FHS) as a magnetically recyclable green catalyst has been developed as mentioned in this paper.Abstract:
An efficient and one-pot multi-component procedure for the preparation of functionalized piperidine derivatives from reactions of aromatic aldehydes, substituted anilines and ethyl acetoacetate in the presence of ferric hydrogen sulfate-supported silica-coated magnetic nanoparticles (NiFe2O4@SiO2-FHS) as a magnetically recyclable green catalyst has been developed. The catalysts show environmentally benign character, which can be easily prepared, stored, and recovered several times without obvious significant loss of activity.read more
Citations
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Synthesis of Highly Functionalized Piperidines Using Polyphosphoric Acid Supported on Silica-coated Magnetic Nanoparticles
TL;DR: The application of magnetic nano particles in the field of catalysis has become a useful area of research as mentioned in this paper and functionalized magnetic nanoparticles (MNPs) have been employed in organic synthesis.
Journal ArticleDOI
One-Pot Pseudo Five Component Synthesis of Biologically Relevant 1,2,6-Triaryl-4-arylamino-piperidine-3-ene-3- carboxylates: A Decade Update
Journal ArticleDOI
Design, preparation and characterization of a new ionic liquid, 1,3-disulfonic acid benzimidazolium chloride, as an efficient and recyclable catalyst for the synthesis of tetrahydropyridine under solvent-free conditions
TL;DR: In this article, 1,3-disulfonic acid benzimidazolium chloride is synthesized, and characterized by studying its FT-IR, 1H NMR, 13C NMR as well as mass spectra.
Journal ArticleDOI
1,3-Disulfonic acid benzimidazolium chloride as an efficient and recyclable ionic liquid catalyst for the synthesis of 3,4-dihydropyrimidine-2-(1H)-ones/thiones
TL;DR: In this paper, 1,3-disulfonic acid benzimidazolium chloride ionic liquid (Dsbim]Cl) was used for the synthesis of 3,4-dihydropyrimidine-2-(1H)-ones/thiones through the one-pot three-component condensation of aromatic aldehydes, urea/thiourea and ethyl acetoacetate under solvent-free conditions.
Journal ArticleDOI
TiCl2·2H2O catalyzed one-pot synthesis of highly functionalized tetrahydropiperidines and evaluation of their antimicrobial activities
Mohsen Abbasi,Seyed Mohammad Seyedi,Hamid Sadeghian,Maryam Akhbari,Mohammadreza Enayaty,Ali Shiri +5 more
TL;DR: In this article, one-pot condensation reaction of ethyl acetoacetate, various substituted benzaldehydes and anilines in the presence of TiCl2·2H2O yields highly functionalized tetrahydropiperidines.
References
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Journal ArticleDOI
Nanoparticles as Recyclable Catalysts: The Frontier between Homogeneous and Heterogeneous Catalysis
TL;DR: The Review presents the recent developments and the use of NP catalysis in organic synthesis, for example, in hydrogenation and C--C coupling reactions, and the heterogeneous oxidation of CO on gold NPs.
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Magnetically Recoverable Chiral Catalysts Immobilized on Magnetite Nanoparticles for Asymmetric Hydrogenation of Aromatic Ketones
TL;DR: Orthogonal nature of the present catalyst immobilization approach should allow the design of other superparamagnetic nanoparticle-supported asymmetric catalysts for a wide range of organic transformations.
Journal ArticleDOI
Organocatalyzed highly atom economic one pot synthesis of tetrahydropyridines as antimalarials.
Mridul Misra,Swaroop Kumar Pandey,Vivek Parashar Pandey,Jyoti Pandey,Renu Tripathi,Rama Pati Tripathi +5 more
TL;DR: A highly atom economic one pot synthesis of tetrahydropyridines was achieved by L-proline/TFA catalysed multicomponent reaction of beta-keto-esters, aromatic aldehydes and anilines.
Journal ArticleDOI
Synthesis and structure-activity relationships of potential anticonvulsants based on 2-piperidinecarboxylic acid and related pharmacophores.
TL;DR: The 2,6-dimethylanilides were the most potent compounds in the MES test in each group of compounds evaluated, and compounds 50 and 75 should be useful leads in the development of agents for the treatment of tonic-clonic and partial seizures in man.
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Efficient one-pot synthesis of functionalized piperidine scaffolds via ZrOCl2·8H2O catalyzed tandem reactions of aromatic aldehydes with amines and acetoacetic esters
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