Journal ArticleDOI
Natural protective glue protein, sericin bioengineered by silkworms: Potential for biomedical and biotechnological applications ☆
TLDR
Sericin promotes proliferation of cells when used as a constituent of cell culture in serum-free media, and supports cell adhesion and proliferation when used in pure form and/or blended in matrices.About:
This article is published in Progress in Polymer Science.The article was published on 2008-10-01. It has received 321 citations till now. The article focuses on the topics: Sericin & Fibroin.read more
Citations
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Silk Materials – A Road to Sustainable High Technology
TL;DR: This review addresses the use of silk protein as a sustainable material in optics and photonics, electronics and optoelectronic applications, and options represent additional developments for this technology platform that compound the broad utility and impact of this material for medical needs.
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3D printing of hydrogels: Rational design strategies and emerging biomedical applications
TL;DR: A review of hydrogel-based biomaterial inks and bioinks for 3D printing can be found in this paper, where the authors provide a comprehensive overview and discussion of the tailorability of material, mechanical, physical, chemical and biological properties.
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Silk Fibroin for Flexible Electronic Devices
TL;DR: Advances in silk-based electronic devices would open new avenues for employing biomaterials in the design and integration of high-performance biointegrated electronics for future applications in consumer electronics, computing technologies, and biomedical diagnosis, as well as human-machine interfaces.
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Composite materials based on silk proteins
John G. Hardy,Thomas Scheibel +1 more
TL;DR: In this paper, a review on the composite structure of silk fibers produced naturally by worms and spiders is presented, followed by the preparation and applications of man-made composite materials (including fibers, films, foams, gels and particulates) incorporating silk proteins in combination with other polymers and/or inorganic particles.
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Silk sericin: A versatile material for tissue engineering and drug delivery.
TL;DR: Recent advancements in the study of silk sericin for application in tissue engineering and drug delivery are summarized.
References
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Journal ArticleDOI
Silk-based biomaterials
Gregory H. Altman,Frank Diaz,Caroline M. Jakuba,Tara Calabro,Rebecca L. Horan,Jingsong Chen,Helen H. Lu,John C. Richmond,David L. Kaplan +8 more
TL;DR: Studies with well-defined silkworm silk fibers and films suggest that the core silk fibroin fibers exhibit comparable biocompatibility in vitro and in vivo with other commonly used biomaterials such as polylactic acid and collagen.
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Silk as a biomaterial
Charu Vepari,David L. Kaplan +1 more
TL;DR: Silks are fibrous proteins with remarkable mechanical properties produced in fiber form by silkworms and spiders that are biocompatible when studied in vitro and in vivo.
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Liquid crystalline spinning of spider silk.
Fritz Vollrath,David P. Knight +1 more
TL;DR: Successful copying of the spider's internal processing and precise control over protein folding, combined with knowledge of the gene sequences of its spinning dopes, could permit industrial production of silk-based fibres with unique properties under benign conditions.
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Mechanism of silk processing in insects and spiders
Hyoung-Joon Jin,David L. Kaplan +1 more
TL;DR: Emulsion formation and micellar structures from aqueous solutions of reconstituted silkworm silk fibroin are identified as a first step in the process to control water and protein–protein interactions and mimics the behaviour of similar native silk proteins in vivo.
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Functionalized silk-based biomaterials for bone formation
TL;DR: RGD covalently decorated silk appears to stimulate osteoblast-based mineralization in vitro and indicates that the proteins serve as suitable bone-inducing matrices.