Journal ArticleDOI
New dimeric stilbenoids from fungal-challenged peanut ( Arachis hypogaea) seeds.
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TLDR
Two new prenylated stilbene dimers named arahypin-6 and arahYPin-7 have been isolated from wounded peanut seeds challenged by an Aspergillus caelatus strain and may play a defensive role against invasive fungi.Abstract:
The peanut plant can resist fungal attacks by producing stilbene-derived phytoalexins. Once understood, such a natural phytoalexin-based mechanism of peanut resistance could be potentially manipulated to obtain fungal-resistant peanut breeding lines. Several simple stilbenoid phytoalexins from peanuts have been reported. However, more complex stilbenoid derivatives such as those that have been reported from other sources and considered important factors in plant defense have not been found in peanuts. The purpose of this research was to isolate and characterize further new oligomeric peanut stilbenoids that may act as phytoalexins. Two new prenylated stilbene dimers named arahypin-6 (3) and arahypin-7 (4) have been isolated from wounded peanut seeds challenged by an Aspergillus caelatus strain. The structures of these new putative phytoalexins were determined by analysis of NMR, MS, and UV spectroscopic data. Together with other known peanut stilbenoids that were also produced in the challenged seeds, these new compounds may play a defensive role against invasive fungi.read more
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Phytoalexins in defense against pathogens
TL;DR: This review focuses on the biosynthesis and regulation of camalexin, and its role in plant defense, and details some of the phytoalexins produced by a range of crop plants from Brassicaceae, Fabaceae, Solanaceae, Vitaceae and Poaceae.
Journal ArticleDOI
Therapeutic Approaches of Resveratrol on Endometriosis via Anti-Inflammatory and Anti-Angiogenic Pathways.
Ana-Maria Dull,Marius Moga,Oana Gabriela Dimienescu,Gabriela Sechel,Victoria Burtea,Costin Vlad Anastasiu +5 more
TL;DR: From the studies reviewed in this paper, it is clear that the anti-inflammatory effect of this natural compound can contribute to the prevention of endometriosis, this phenolic compound now being considered a new innovative drug in the prevention and treatment of this disease.
Journal ArticleDOI
Chemical Composition and Biological Activities of Arachis Species
TL;DR: An overview of the chemical composition, focusing on secondary metabolites, and of the biological activity of A. hypogaea is given to stimulate new studies about species of the Arachis genus.
Journal ArticleDOI
Purification of resveratrol, arachidin-1, and arachidin-3 from hairy root cultures of peanut (Arachis hypogaea) and determination of their antioxidant activity and cytotoxicity
Julie A. Abbott,Fabricio Medina-Bolivar,Elizabeth M. Martin,Abigail S. Engelberth,Hector Villagarcia,Edgar C. Clausen,Danielle Julie Carrier +6 more
TL;DR: The integration of a production and purification system for the manufacturing of A. hypogaea‐derived stilbenoids is demonstrated and resveratrol exhibited no cytotoxicity to either cell line.
Journal ArticleDOI
Impact of Environmental Factors on Stilbene Biosynthesis.
TL;DR: In this paper, the authors present the most updated knowledge of the stilbene biosynthetic pathway, also focusing on the role of several environmental factors in eliciting stilbenes biosynthesis.
References
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Mohammad Athar,Jung Ho Back,Xiuwei Tang,Kwang Ho Kim,Levy Kopelovich,David R. Bickers,Arianna L. Kim +6 more
TL;DR: The current preclinical and mechanistic data available and resveratrol's anticancer effects are assessed to support its potential as an anticancer agent in human populations are discussed.
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Journal ArticleDOI
Phytoalexins from the Vitaceae: biosynthesis, phytoalexin gene expression in transgenic plants, antifungal activity, and metabolism.
Philippe Jeandet,Anne-Céline Douillet-Breuil,Roger Bessis,S. Debord,M. Sbaghi,Marielle Adrian +5 more
TL;DR: Particular attention has been given here to stilbene phytoalexins produced by Vitaceae, specifically, their pathway of biosynthesis (including stilBenephytoalxin gene transfer experiments to other plants and their biological activity together with fungal metabolism.
Journal ArticleDOI
A new class of phytoalexins from grapevines.
P. Langcake,R. J. Pryce +1 more
TL;DR: A novel phytoalexins isolated from grapevine leaves are oligomeric forms of the trihydroxy stilbene resveratrol, which co-occurs with these compounds, and their characterization as a resver atrol dimer is described.
Journal ArticleDOI
Bioactivity of Resveratrol
TL;DR: Scientific information summarized in this review supports the many potential health benefits of resveratrol; however, further understanding of the bioavailability, metabolism, and cellular effects of res veratrol is necessary.