Nonlinear formulation of the magnetic field to source relationship for robust quantitative susceptibility mapping.
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TLDR
This nonlinear QSM method reduced salt and pepper noise or checkerboard pattern in high susceptibility regions in healthy subjects and markedly reduced artifacts in patients with intracerebral hemorrhages.Abstract:
Quantitative susceptibility mapping (QSM) opens the door for measuring tissue magnetic susceptibility properties that may be important biomarkers, and QSM is becoming an increasingly active area of scientific and clinical investigations. In practical applications, there are sources of errors for QSM including noise, phase unwrapping failures, and signal model inaccuracy. To improve the robustness of QSM quality, we propose a nonlinear data fidelity term for frequency map estimation and dipole inversion to reduce noise and effects of phase unwrapping failures, and a method for model error reduction through iterative tuning. Compared with the previous phase based linear QSM method, this nonlinear QSM method reduced salt and pepper noise or checkerboard pattern in high susceptibility regions in healthy subjects and markedly reduced artifacts in patients with intracerebral hemorrhages.read more
Citations
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Texture analyses of quantitative susceptibility maps to differentiate Alzheimer's disease from cognitive normal and mild cognitive impairment.
Eo-Jin Hwang,Hyug-Gi Kim,Danbi Kim,Hak Young Rhee,Chang-Woo Ryu,Tian Liu,Yi Wang,Geon-Ho Jahng +7 more
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Karen D. Ersche,Julio Acosta-Cabronero,P.S. Jones,Hisham Ziauddeen,R. P. L. van Swelm,Coby M. Laarakkers,R Raha-Chowdhury,Guy B. Williams +7 more
TL;DR: The findings show that iron dysregulation occurs in cocaine addiction and suggest that it arises consequent to chronic cocaine use, and the value of iron levels in the brain and periphery as biomarkers of vulnerability to, as well as progression and response to treatment of cocaine addiction is determined.
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Quantitative Susceptibility Mapping of Intracerebral Hemorrhages at Various Stages
Shixin Chang,Jingwei Zhang,Tian Liu,Apostolos John Tsiouris,Jian Shou,Thanh D. Nguyen,Dana Leifer,Yi Wang,Ilhami Kovanlikaya +8 more
TL;DR: To investigate the magnetic susceptibility of intracerebral hemorrhages at various stages by applying quantitative susceptibility mapping (QSM).
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The spatiotemporal changes in dopamine, neuromelanin and iron characterizing Parkinson's disease
Emma Biondetti,Emma Biondetti,Mathieu Santin,Mathieu Santin,Romain Valabregue,Romain Valabregue,Graziella Mangone,Rahul Gaurav,Rahul Gaurav,Nadya Pyatigorskaya,Nadya Pyatigorskaya,Matthew Hutchison,Lydia Yahia-Cherif,Lydia Yahia-Cherif,Nicolas Villain,Marie-Odile Habert,I. Arnulf,I. Arnulf,Smaranda Leu-Semenescu,Pauline Dodet,Miquel Vila,Jean-Christophe Corvol,M. Vidailhet,M. Vidailhet,Stéphane Lehéricy +24 more
TL;DR: In this paper, the authors assessed the spatiotemporal ordering of such changes and relationships in the sensorimotor, associative and limbic territories of the nigrostriatal system.
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Susceptibility Weighted Imaging and Mapping of Micro-Hemorrhages and Major Deep Veins after Traumatic Brain Injury
Jun Liu,Jun Liu,Shuang Xia,Robin A. Hanks,Natalie Wiseman,Changya Peng,Shunke Zhou,E. Mark Haacke,Zhifeng Kou +8 more
TL;DR: Results show that SWIM could be used to differentiate hemorrhages from veins in TBI patients in a semi-automated manner with reasonable sensitivity and specificity, and a larger cohort will be needed to validate these findings.
References
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