Journal ArticleDOI
Noradrenergic innervation of cerebral cortex: widespread effects of local cortical lesions.
TLDR
The trajectory of the intracortical noradrenergic fibers has been characterized by histochemical analysis following the production of cortical lesions in the rate to show a medial to lateral topographic relationship between deep longitudinally running fibers and overlying cortex.Abstract:
The trajectory of the intracortical noradrenergic fibers has been characterized by histochemical analysis following the production of cortical lesions in the rate. A large group of noradrenergic fibers enters the cortex at the frontal pole and proceeds caudally through the deep layers of dorsolateral cortex. Branches arise from these longitudinally directed fibers and form a uniform pattern of innervation throughout lateral cortex. Because these fibers travel long distances rostrocaudally within the gray matter, a large area of cortex can be deprived of noradrenergic innervation by a relatively small lesion of frontal cortex. The medial and lateral cortex can be selectively and differentially denervated of noradrenergic fibers, and there is a medial to lateral topographic relationship between deep longitudinally running fibers and overlying cortex.read more
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Book
The prefrontal cortex
TL;DR: The Prefrontal Cortex, Fifth Edition, provides users with a thoroughly updated version of this comprehensive work that has historically served as the classic reference on this part of the brain.
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Hippocampus, space, and memory
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Decision making, the P3, and the locus coeruleus-norepinephrine system.
TL;DR: The theoretical framework emerging from this research synthesis suggests that the P3 reflects the response of the LC-NE system to the outcome of internal decision-making processes and the consequent effects of noradrenergic potentiation of information processing.
References
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Receptive fields, binocular interaction and functional architecture in the cat's visual cortex
David H. Hubel,Torsten N. Wiesel +1 more
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Journal ArticleDOI
Ascending Monoamine Neurons to the Telencephalon and Diencephalon
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Journal Article
The organization of the ascending catecholamine neuron systems in the rat brain as revealed by the glyoxylic acid fluorescence method.
O Lindvall,A Björklund +1 more
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Ascending projections of the locus coeruleus in the rat. II. Autoradiographic study
TL;DR: The ascending projections of the locus coeruleus were studied using an autoradiographic method and the largest projections are to the lateral hypothalamic area, periventricular nucleus, supraoptic nucleus and paraventricul nucleus.