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Open AccessJournal ArticleDOI

Nucleotide sequence of cloned rat serum albumin messenger RNA

Thomas D. Sargent, +2 more
- 01 Jan 1981 - 
- Vol. 78, Iss: 1, pp 243-246
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TLDR
The nucleotide sequences of the recombinant DNA inserts of three bacterial plasmid clones containing nearly all of the rat serum albumin mRNA have been determined and reveal a pattern of repeated internal homology that confirms the "intragenic triplication" model of albumin evolution.
Abstract
The nucleotide sequences of the recombinant DNA inserts of three bacterial plasmid clones containing nearly all of the rat serum albumin mRNA have been determined. A statistical analysis of the nucleotide sequence reveals a pattern of repeated internal homology that confirms the "intragenic triplication" model of albumin evolution.

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Atomic structure and chemistry of human serum albumin.

TL;DR: The three-dimensional structure of human serum albumin has been determined crystallographically to a resolution of 2.8 Å and should provide insight into future pharmacokinetic and genetically engineered therapeutic applications of serumalbumin.
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Structure of serum albumin.

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Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.

TL;DR: Observations raise the possibility that the synthesis of C/EBP may be responsive to humoral factors and that modulation in C/ EBP expression might mediate coordinated changes in gene expression that facilitate adaptive challenges met during development or during the fluctuating physiological states of adult life.
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