Journal ArticleDOI
Numerical Simulation of Flow in a Screw-Type Blood Pump
TLDR
The study shows that high shear levels are confined to small regions within the channel cross-section, but the circulatory nature of the flow causes an increased percentage of blood elements to pass through the high sheer regions, and increases the likelihood of cell damage.Abstract:
This study presents a numerical investigation of the flow field in a screw pump designed to circulate biological fluid such as blood. A simplified channel flow model is used to allow analysis using a Cartesian set of coordinates. Finite analytic (FA) numerical simulation of the flow field inside the channel was performed to study the influence of Reynolds number and pressure gradient on velocity distribution and shear stresses across the channel cross-section. Simulation results were used to predict flow rates, circulatory flow and the shear stresses, which are known to be related to the level of red blood cell damage (hemolysis) caused by the pump. The study shows that high shear levels are confined to small regions within the channel cross-section, but the circulatory nature of the flow causes an increased percentage of blood elements to pass through the high shear regions, and increases the likelihood of cell damage.read more
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References
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Journal ArticleDOI
Red Blood Cell Damage by Shear Stress
TL;DR: It is shown that the exposure time-shear stress plane is divided into two distinct regimes, and in the regime of relatively low stresses and exposure times there is relatively little damage, and the damage is dominated by solid surface interaction effects.
Journal Article
In vivo evaluation of a peripheral vascular access axial flow blood pump.
TL;DR: The data indicates that the device may provide full support for a failing left ventricle with minimal trauma or risk and the hardware was typically free of deposits.
Journal ArticleDOI
A miniature implantable axial flow ventricular assist device
TL;DR: The performance characteristics of the pump implanted in calves up to 90 days are highly gratifying, particularly in terms of pump output of 5 L/min, an index of hemolysis well within normal limits, and absence of thromboembolism.
Journal ArticleDOI
Developments in the analysis of steady screw extrusion of polymers
TL;DR: A review of theoretical and experimental work on the single screw extrusion process for polymers is given in this paper, where a detailed consideration is given to the many published theoretical models of solids conveying, melting and melt flow in the channel of a plasticating extruder.
Journal ArticleDOI
LVAD Power Delivery: A Percutaneous Approach to Avoid Infection
TL;DR: The combination of rigid fixation and highly vascular scalp skin reduces the risk of percutaneous driveline infection and may solve an important outstanding problem in use of left ventricular assist devices.