Journal ArticleDOI
Occupational asbestos exposure and risk of pleural mesothelioma, lung cancer, and laryngeal cancer in the prospective netherlands cohort study
Nadine S M Offermans,Roel Vermeulen,Alex Burdorf,R Alexandra Goldbohm,Timo Kauppinen,Hans Kromhout,Piet A. van den Brandt +6 more
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TLDR
Asbestos levels encountered at the lower end of the exposure distribution may be associated with an increased risk of pleural mesothelioma, lung cancer, and laryngeal cancer.Abstract:
OBJECTIVE:: To study the association between occupational asbestos exposure and pleural mesothelioma, lung cancer, and laryngeal cancer, specifically addressing risk associated with the lower end of the exposure distribution, risk of cancer subtypes, and the interaction between asbestos and smoking. METHODS:: Using the Netherlands Cohort Study (n = 58,279 men, aged 55 to 69 years), asbestos exposure was estimated by linkage to job-exposure matrices. After 17.3 years of follow-up, 132 pleural mesothelioma, 2324 lung cancer, and 166 laryngeal cancer cases were available. RESULTS:: The multivariable-adjusted model showed overall positive associations between all levels of asbestos exposure and mesothelioma, lung cancer, and laryngeal cancer. Lung adenocarcinoma and glottis cancer showed only a positive association after prolonged higher asbestos exposure (hazard ratio per 10 years increment, 1.43 [95% confidence interval, 1.06 to 1.93] and 1.95 [95% confidence interval, 1.36 to 2.80], respectively). There was no statistically significant interaction between asbestos and smoking. CONCLUSIONS:: Asbestos levels encountered at the lower end of the exposure distribution may be associated with an increased risk of pleural mesothelioma, lung cancer, and laryngeal cancer. © 2013 by American College of Occupational and Environmental Medicine.read more
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Malignant Mesothelioma and Its Non-Asbestos Causes
TL;DR: A review of non-asbestos causes for malignant mesothelioma is provided to provide a review of alternative etiologies that account for a small proportion of tumors.
Journal ArticleDOI
Prevention of Asbestos-Related Disease in Countries Currently Using Asbestos
Daniela Marsili,Benedetto Terracini,Vilma Sousa Santana,Juan Pablo Ramos-Bonilla,Roberto Pasetto,Agata Mazzeo,Dana Loomis,Pietro Comba,Eduardo Algranti +8 more
TL;DR: An agenda for an international cooperation framework dedicated to foster a public health response to asbestos is suggested, including new epidemiological studies for assessing the health impact of asbestos in specific contexts; socio-cultural and economic analyses for contributing to identifying stakeholders and to address both the local and global implications of asbestos diffusion.
Journal ArticleDOI
Asbestos, Smoking and Lung Cancer: An Update.
TL;DR: It is concluded that the mechanism of lung cancer causation induced by the interdependent coaction of asbestos fibers and tobacco smoke at a biological level is a multistage stochastic process with both agents acting conjointly at all times.
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Trend analysis of anonymised pooled urine from portable street urinals in central London identifies variation in the use of novel psychoactive substances
TL;DR: This study demonstrates that analysis of anonymous pooled urine samples from stand-alone urinals can be used to detect and monitor trends in the use of classical recreational drugs and NPS in a large city centre over time.
Journal ArticleDOI
Mapping Asbestos-Cement Roofing with Hyperspectral Remote Sensing over a Large Mountain Region of the Italian Western Alps
Federico Frassy,Gabriele Candiani,Marco Rusmini,Pieralberto Maianti,Andrea Marchesi,Francesco Rota Nodari,Giorgio Dalla Via,Carlo Albonico,Marco Gianinetto +8 more
TL;DR: In this paper, the authors describe the quantitative mapping of asbestos-cement covers over a large mountainous region of Italian Western Alps using the Multispectral Infrared and Visible Imaging Spectrometer sensor.
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