Proceedings ArticleDOI
Optical band gap and crystallite size investigations of anticancer drug loaded ZnO nanoparticles
Deepak Kumar,Samanwita Pal +1 more
- Vol. 2142, Iss: 1, pp 180004
TLDR
In this paper, the authors developed and characterized zinc oxide (ZnO) nanoparticles as a carrier for various anti-cancerous drugs viz. 5-Fluorouracil (5-FU), Doxorubicin (DOX) and Daunorubricin (DNR).Abstract:
The present study aims at the development and characterization of zinc oxide (ZnO) nanoparticles as a carrier for various anti-cancerous drugs viz. 5-Fluorouracil (5-FU), Doxorubicin (DOX) and Daunorubicin (DNR). ZnO nanoparticles were prepared by standard precipitation method. The measurement of optical band gap using UV-Visible Diffuse Reflectance Spectroscopy (DRS) analysis reveals the lowering of ZnO band gap after the drug loading. Crystallite size of free and drug loaded ZnO nanoparticles were determined using X-ray Diffraction (XRD) analysis. The crystallite size of ZnO nanoparticles increases after the drug loading. Both the techniques confirm the adsorption of drug molecules on ZnO surface.read more
Citations
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Journal ArticleDOI
Metal-based nano-delivery platform for treating bone disease and regeneration
TL;DR: The merits and demerits of the current metal-based drug-loaded nanomaterial platforms are critically discussed, and the challenges faced to realize their future applications are summarized.
Journal ArticleDOI
Investigation of Adsorption Behavior of Anticancer Drug on Zinc Oxide Nanoparticles: A Solid State NMR and Cyclic Voltammetry (CV) Analysis.
Deepak Kumar,C. Hepsibah Priyadarshini,V. Sudha,Jositta Sherine,S. Harinipriya,Samanwita Pal +5 more
TL;DR: In this article, a set of anticancer drugs namely 5-fluorouracil (5-FU), doxorubicin (DoXorUBicin), and daunorubicain (Daunorubeicin) on ZnO nanoparticles (ZnO NPs) were proposed as drug delivery systems employing solid state (ss) NMR, FTIR and Cyclic Voltammetry (CV) analysis.
References
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