Outpatient antibiotic use and prevalence of antibiotic-resistant pneumococci in France and Germany: a sociocultural perspective.
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TLDR
The prevalence of penicillin-nonsusceptible pneumococci is sharply divided between France and Germany, and the overarching importance of a sociocultural approach to preventing antibiotic resistance in the community is emphasized.Abstract:
The prevalence of penicillin-nonsusceptible pneumococci is sharply divided between France (43%) and Germany (7%). These differences may be explained on different levels: antibiotic- prescribing practices for respiratory tract infections; patient-demand factors and health-belief differences; social determinants, including differing child-care practices; and differences in regulatory practices. Understanding these determinants is crucial for the success of possible interventions. Finally, we emphasize the overarching importance of a sociocultural approach to preventing antibiotic resistance in the community.read more
Citations
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Jean-Christophe Lucet,Marie-Hélène Nicolas-Chanoine,Marie-Hélène Nicolas-Chanoine,Carine Roy,Oscar Riveros-Palacios,Sylvain Diamantis,Sylvain Diamantis,Jennifer Le Grand,Emmanuelle Papy,Christophe Rioux,Bruno Fantin,Bruno Fantin,Agnès Lefort,Agnès Lefort,Philippe Ravaud +14 more
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References
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TL;DR: It is suggested that a low daily dose and a long duration of treatment with an oral beta-lactam contribute to the selective pressure in promoting pharyngeal carriage of penicillin-resistant S pneumoniae.