Outpatient antibiotic use and prevalence of antibiotic-resistant pneumococci in France and Germany: a sociocultural perspective.
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TLDR
The prevalence of penicillin-nonsusceptible pneumococci is sharply divided between France and Germany, and the overarching importance of a sociocultural approach to preventing antibiotic resistance in the community is emphasized.Abstract:
The prevalence of penicillin-nonsusceptible pneumococci is sharply divided between France (43%) and Germany (7%). These differences may be explained on different levels: antibiotic- prescribing practices for respiratory tract infections; patient-demand factors and health-belief differences; social determinants, including differing child-care practices; and differences in regulatory practices. Understanding these determinants is crucial for the success of possible interventions. Finally, we emphasize the overarching importance of a sociocultural approach to preventing antibiotic resistance in the community.read more
Citations
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Antimicrobial drug use and resistance in Europe.
Nienke van de Sande-Bruinsma,Hajo Grundmann,Didier Verloo,E Tiemersma,J. Monen,Herman Goossens,Matus Ferech +6 more
TL;DR: Routine surveillance data indicate a relation between use and resistance and support interventions designed to reduce antimicrobial consumption at a national level in Europe.
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Antibiotic selection pressure and resistance in Streptococcus pneumoniae and Streptococcus pyogenes.
TL;DR: This study correlated outpatient antibiotic use with prevalence of penicillin-nonsusceptible Streptococcus pneumoniae, macrolide-resistant S. pneumoniae (MRSP), and macrolides- resistant S. pyogenes (MRGAS) in 20 countries to find out how antibiotic selection pressure on a national level affectsStreptococcal resistance.
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Ready for a world without antibiotics? The Pensieres Antibiotic Resistance Call to Action.
Jean Carlet,Vincent Jarlier,Stéphan Juergen Harbarth,Andreas Voss,Herman Goossens,Didier Pittet +5 more
TL;DR: Bundles of measures that must be implemented simultaneously and worldwide are presented in this document and include antibiotics, which represent a treasure for humanity, must be protected and considered as a special class of drugs.
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Antibiotic prescribing in hospitals: a social and behavioural scientific approach.
TL;DR: How the volume and appropriateness of antibiotic use in hospitals vary between countries, hospitals, and physicians is described.
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Antimicrobial resistance determinants and future control.
TL;DR: Determinants likely to influence the future epidemiology and health impact of antimicrobial-resistant infections are described and will ultimately optimize preventive strategies for an unpredictable future.
References
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Cultural and economic factors that (mis)shape antibiotic use: the nonpharmacologic basis of therapeutics.
Jerry Avorn,Daniel H. Solomon +1 more
TL;DR: A prescription for an antibiotic is often seen as the quickest way to end the visit of a patient with possible infectious symptoms, and this strategy creates a paradoxical outcome in the current environment, which is so preoccupied with throughput.
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Antibiotic therapy of community respiratory tract infections: strategies for optimal outcomes and minimized resistance emergence
P. Ball,Fernando Baquero,O. Cars,Thomas M. File,Javier Garau,Keith P. Klugman,Donald E. Low,Ethan Rubinstein,Richard Wise +8 more
TL;DR: Prescribing should be based on pharmacodynamic principles that predict efficacy, bacterial eradication and prevention of resistance emergence, and Pharmacoeconomic analyses confirm that bacteriologically more effective antibiotics can reduce overall management costs, particularly with respect to consequential morbidity and hospital admission.
Journal ArticleDOI
Effect of short-course, high-dose amoxicillin therapy on resistant pneumococcal carriage: a randomized trial.
Stephanie J. Schrag,Chabela Peña,Josefina Fernández,Jacqueline Sánchez,Virgen Gomez,Eddy Pérez,Jesús M. Feris,Richard E. Besser +7 more
TL;DR: In this article, a randomized trial was conducted to determine whether short-course, high-dose amoxicillin therapy reduces the risk of post-treatment resistant pneumococcal carriage among children with respiratory tract infections.
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National differences in incidence of acute mastoiditis: relationship to prescribing patterns of antibiotics for acute otitis media?
TL;DR: The incidence rate of acute mastoiditis in the Netherlands is higher than in many countries with higher antibiotic prescription rates and the potential benefits of restricted use of antibiotics may be associated with a somewhat higher incidence.
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Geographical differences in invasive pneumococcal disease rates and serotype frequency in young children.
TL;DR: It is postulated that mild IPD is probably underdiagnosed and under-reported in western Europe, and those serotypes found at similar frequencies in both regions are virulent and rarely cause mild disease.